随着天然产物分离鉴定的仪器和技术的快速发展，在过去的几十年里被发现的天然有机过氧化物的数量呈迅速增加之势。然而，该类化合物的合成研究却大大落后于分离鉴定；到目前为止，已知过氧天然产物中仍只有很小一部分被合成过，而且大多数合成还是外消旋的。这是因为在有机结构中引入过氧键的方法十分有限，过氧键十分脆弱也是原因之一。开展对有机过氧化物（包括天然的及类天然的）合成研究还是十分有必要的，特别是在当今 --- 对过氧化物类药物（例如青蒿素）的兴趣不断升温的时代。

In the last decades with the aid of ever-improving instruments and techniques for isolation and characterization of natural products, the number of identified natural organic peroxides has been on rapid increase. However, the synthetic studies still lag far behind. To date, only a small portion of naturally occurring organic peroxides have been synthesized. And in most cases the syntheses were achieved in a racemic manner, as a result of serious lack of effective methods for installation of peroxy bonds into organic structures. The fragile nature of peroxy bonds also contributes. Investigations into synthesis of such organic peroxides, both natural and natural-like ones, are thus fully warranted, especially taking into consideration the rising interests in peroxide drugs exemplified by qinghaosu (artemisinin).