Fruit, vegetable, and antioxidant intakes are lower in older adults with depression.
Fruit, vegetable, and antioxidant intakes are lower in older adults with depression.
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DOI：
10.1016/j.jand.2012.08.026
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发表时间：
2012-12
影响因子：
4.8
通讯作者：
Steffens, David C.
中科院分区：
文献类型：
--
作者：
Payne, Martha E.;Steck, Susan E.;George, Rebecca R.;Steffens, David C.
研究表明，抑郁症与抗氧化剂水平和氧化应激之间存在关联，但通常不包括摄入抗氧化剂和富含抗氧化剂的水果和蔬菜。本研究调查了一组老年人中临床诊断的抑郁症与抗氧化剂、水果和蔬菜摄入量之间的横断面关联。抗氧化剂，水果和蔬菜的摄入量在278名老年参与者（144名抑郁症患者，134名无抑郁症患者）中进行了评估，使用1999年至2007年期间进行的Block 1998食物频率问卷。所有参与者的年龄都在60岁或以上。抑郁症患者维生素C、叶黄素和隐黄素的摄入量显著低于对照组（p<0.05）。此外，水果和蔬菜的消费，抗氧化剂摄入量的主要决定因素，在抑郁症患者中较低。在多变量模型中，控制年龄，性别，教育，血管合并症评分，体重指数，总膳食脂肪，酒精，维生素C，隐黄素，水果和蔬菜仍然显着。膳食补充剂中的抗氧化剂与抑郁症无关。抗氧化剂、水果和蔬菜的摄入量在晚年抑郁症患者中低于对照组。这些关联可以部分解释老年抑郁症患者心血管疾病风险升高的原因。此外，这些发现指出了抗氧化食物来源而不是膳食补充剂的重要性。
Studies have shown an association between depression and both antioxidant levels and oxidant stress, but generally have not included intakes of antioxidants and antioxidant-rich fruits and vegetables. The present study examined the cross-sectional associations between clinically-diagnosed depression and intakes of antioxidants, fruits and vegetables in a cohort of older adults. Antioxidant, fruit and vegetable intakes were assessed in 278 elderly participants (144 with depression, 134 without depression) using a Block 1998 food frequency questionnaire, which was administered between 1999 and 2007. All participants were age 60 years or over. Vitamin C, lutein and cryptoxanthin intakes were significantly lower among depressed individuals than in comparison participants (p<0.05). In addition, fruit and vegetable consumption, a primary determinant of antioxidant intake, was lower in depressed individuals. In multivariable models, controlling for age, sex, education, vascular comorbidity score, body mass index, total dietary fat, and alcohol, vitamin C, cryptoxanthin, fruits and vegetables remained significant. Antioxidants from dietary supplements were not associated with depression. Antioxidant, fruit and vegetable intakes were lower in individuals with late-life depression than in comparison participants. These associations may partially explain the elevated risk of cardiovascular disease among older depressed individuals. In addition, these findings point to the importance of antioxidant food sources rather than dietary supplements.
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影响因子：
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