Hierarchical Fabrication of Engineered Vascularized Bone Biphasic Constructs via Dual 3D Bioprinting: Integrating Regional Bioactive Factors into Architectural Design.
Hierarchical Fabrication of Engineered Vascularized Bone Biphasic Constructs via Dual 3D Bioprinting: Integrating Regional Bioactive Factors into Architectural Design.
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DOI:
10.1002/adhm.201600505
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发表时间:
2016-09
影响因子:
10
通讯作者:
Zhang, Lijie Grace
中科院分区:
文献类型:
--
作者:
Cui, Haitao;Zhu, Wei;Nowicki, Margaret;Zhou, Xuan;Khademhosseini, Ali;Zhang, Lijie Grace
关键词:
In the past three decades, tissue engineering has made great progress in fabricating various artificial tissues with simple structures, achieving partially functional restoration in fundamental research and in clinical applications.[1, 2] However, the vast majority of tissue types possess hierarchical, complicated characteristics both in structure and function.[1, 3] Continuous efforts toward understanding the complex biological mechanism of the regeneration process provide new knowledge for engineering the restoration of functional tissue. Effectively recapitulating the intrinsic complexity of native tissues is dependent on
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