Magnesium enhances exercise performance via increasing glucose availability in the blood, muscle, and brain during exercise.
Magnesium enhances exercise performance via increasing glucose availability in the blood, muscle, and brain during exercise.
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DOI：
10.1371/journal.pone.0085486
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发表时间：
2014
期刊：
影响因子：
3.7
通讯作者：
Wang MF
中科院分区：
文献类型：
--
作者：
Chen HY;Cheng FC;Pan HC;Hsu JC;Wang MF
外周和中枢神经系统中的葡萄糖动员和利用在运动期间是重要的，并且负责运动功效。镁（Mg）参与能量产生并在运动表现中发挥作用。本研究采用自动采血和微透析相结合的方法，探讨镁对运动大鼠肌肉、血液和脑组织中葡萄糖和乳酸水平动态变化的影响。Sprague-Dawley大鼠用生理盐水或硫酸镁（MgSO4，90 mg/kg，i.p.）跑台运动前30 min（20 m/min，60 min）。我们的研究结果表明，肌肉，血液和大脑的葡萄糖水平在运动过程中立即增加，然后在两组的恢复期逐渐下降到接近基础水平。这些葡萄糖水平在Mg组中显著增加至约两倍（P <0.05）。运动过程中，两组大鼠肌肉、血液和脑组织中乳酸水平均迅速显著升高，其中镁组大鼠脑组织乳酸水平进一步升高（P <0.05）。两组的乳酸水平在运动后都显著下降。总之，镁增强了外周和中枢系统中的葡萄糖利用率，并增加了运动过程中肌肉中的乳酸清除率。
Glucose mobilization and utilization in the periphery and central nervous system are important during exercise and are responsible for exercise efficacy. Magnesium (Mg) is involved in energy production and plays a role in exercise performance. This study aimed to explore the effects of Mg on the dynamic changes in glucose and lactate levels in the muscle, blood and brain of exercising rats using a combination of auto-blood sampling and microdialysis. Sprague-Dawley rats were pretreated with saline or magnesium sulfate (MgSO4, 90 mg/kg, i.p.) 30 min before treadmill exercise (20 m/min for 60 min). Our results indicated that the muscle, blood, and brain glucose levels immediately increased during exercise, and then gradually decreased to near basal levels in the recovery periods of both groups. These glucose levels were significantly enhanced to approximately two-fold (P<0.05) in the Mg group. Lactate levels in the muscle, blood, and brain rapidly and significantly increased in both groups during exercise, and brain lactate levels in the Mg group further elevated (P<0.05) than those in the control group during exercise. Lactate levels significantly decreased after exercise in both groups. In conclusion, Mg enhanced glucose availability in the peripheral and central systems, and increased lactate clearance in the muscle during exercise.
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影响因子：
3
作者：
Cheng, Shiu-Min;Yang, Lin-Lan;Cheng, Fu-Chou
通讯作者：
Cheng, Fu-Chou
影响因子：
3
作者：
Cheng, Shiu-Min;Yang, Dar-Yu;Cheng, Fu-Chou
通讯作者：
Cheng, Fu-Chou
影响因子：
3.4
作者：
Golf, SW;Bender, S;Grüttner, J
通讯作者：
Grüttner, J
影响因子：
4.2
作者：
Choi, IY;Seaquist, ER;Gruetter, R
通讯作者：
Gruetter, R
DOI：
10.1046/j.1365-201x.2001.00859.x
发表时间：
2001-10-01
期刊：
ACTA PHYSIOLOGICA SCANDINAVICA
影响因子：
--
作者：
Béquet, F;Gomez-Merino, D;Guezennec, CY
通讯作者：
Guezennec, CY