Variation in the AvrSr35 gene determines Sr35 resistance against wheat stem rust race Ug99.
Variation in the AvrSr35 gene determines Sr35 resistance against wheat stem rust race Ug99.
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DOI：
10.1126/science.aao7294
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发表时间：
2017-12-22
期刊：
影响因子：
--
通讯作者：
Akhunov E
中科院分区：
文献类型：
--
作者：
Salcedo A;Rutter W;Wang S;Akhunova A;Bolus S;Chao S;Anderson N;De Soto MF;Rouse M;Szabo L;Bowden RL;Dubcovsky J;Akhunov E
Puccinia graminis f。识别SR35空气电力所需的名为AVRSR35的真菌基因。 SR35和触发免疫响应。靶标，以及小麦免疫的分子决定剂的表征。
Puccinia graminis f. sp. tritici (Pgt) causes wheat stem rust, a devastating fungal disease. The Sr35 resistance gene confers immunity against this pathogen’s most virulent races, including Ug99. We used comparative whole-genome sequencing of chemically mutagenized and natural Pgt isolates to identify a fungal gene named AvrSr35 that is required for Sr35 avirulence. The AvrSr35 gene encodes a secreted protein capable of interacting with Sr35 and triggering the immune response. We show that the origin of Pgt isolates virulent on Sr35 is associated with the nonfunctionalization of the AvrSr35 gene by the insertion of a mobile element. The discovery of AvrSr35 provides a new tool for Pgt surveillance, identification of host susceptibility targets, and characterization of the molecular determinants of immunity in wheat.
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影响因子：
4.4
作者：
Rutter WB;Salcedo A;Akhunova A;He F;Wang S;Liang H;Bowden RL;Akhunov E
通讯作者：
Akhunov E
影响因子：
4.5
作者：
Pretorius, Z. A.;Singh, R. P.;Payne, T. S.
通讯作者：
Payne, T. S.
影响因子：
9.5
作者：
Elmore JM;Lin ZJ;Coaker G
通讯作者：
Coaker G
影响因子：
4.4
作者：
Cantu D;Segovia V;MacLean D;Bayles R;Chen X;Kamoun S;Dubcovsky J;Saunders DG;Uauy C
通讯作者：
Uauy C
DOI：
10.1073/pnas.1019315108
发表时间：
2011-05-31
影响因子：
11.1
作者：
Duplessis, Sebastien;Cuomo, Christina A.;Martin, Francis
通讯作者：
Martin, Francis