Effects of coronary occlusion on cardiac and body surface PQRST isoarea maps of dogs with abnormal activation simulating left bundle branch block.
Effects of coronary occlusion on cardiac and body surface PQRST isoarea maps of dogs with abnormal activation simulating left bundle branch block.
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冠状动脉闭塞对模拟左束支传导阻滞异常激活的狗心脏和体表 PQRST 等面积图的影响。
DOI：
10.1161/01.cir.77.6.1414
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发表时间：
1988
期刊：
影响因子：
37.8
通讯作者：
Haws,CW
中科院分区：
文献类型：
--
作者：
Hirai,M;Burgess,MJ;Haws,CW
本文在9只开胸和6只闭胸犬上研究了在左束分支传导阻滞的情况下，通过分析心脏和体表的PQT等面积图来检测心肌梗塞的可能性。记录期间室上性驱动或右心房加右心室起搏在控制期和间隔长达10小时后，左前降支冠状动脉闭塞。右心室起搏模拟左束支分支传导阻滞。心肌梗死用三苯基四氮唑染色。冠状动脉阻断前后，室上性驱动和右房加右室起搏时的PQT面积均高度相关。冠状动脉闭塞后的PQ图显示，开胸动物心脏表面缺血区和闭胸动物左前胸上方有一个强极。在闭塞的最初1至2小时内，PQ极为阳性，数小时后变为阴性。研究结果表明，局部异常，由于缺血和梗死是明显的身体和心脏表面的PQT等面积图的室上性复合体和右心室起搏复合体。研究结果表明，在异常激动的情况下，如左束分支阻滞，PQT等面积图可能有助于缺血或梗死心肌的识别和定位。
The possibility of detecting myocardial infarction in the presence of left bundle branch block by analysis of cardiac and body surface PQRST isoarea maps was studied in nine open-chest and six closed-chest dogs. Recordings were taken during supraventricular drive or right atrial plus right ventricular pacing in control periods and at intervals for up to 10 hr after left anterior descending coronary artery occlusion. Right ventricular pacing was used to simulate left bundle branch block. Myocardial infarction was documented with triphenyl tetrazolium staining. The PQRST areas during supraventricular drive and right atrial plus right ventricular pacing were highly correlated to each other both before and after coronary occlusion. The PQRST isoarea maps after coronary occlusion showed a strong pole overlying the ischemic area on the cardiac surface in open-chest animals and over the left anterior thorax in closed-chest animals. The PQRST pole was positive during the first 1 to 2 hr of occlusion and became negative after several hours. The findings demonstrate that localized abnormalities due to ischemia and infarction are manifest in body and cardiac surface PQRST isoarea maps of both supraventricular complexes and right ventricular paced complexes. The findings suggest that PQRST isoarea maps may aid in identification and localization of ischemic or infarcted myocardium in the setting of abnormal activation such as left bundle branch block.
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影响因子：
4.8
作者：
SIMONSON, E;SCHMITT, OH;BAKKEN, EE
通讯作者：
BAKKEN, EE
室性心律失常的脆弱性：通过体表电位测绘进行评估。
影响因子：
37.8
作者：
M. Gardner;T. Montague;C. Armstrong;B. Horáček;E. Smith
通讯作者：
E. Smith
完全性左束支传导阻滞：可以诊断心肌梗塞吗？
影响因子：
3.5
作者：
Frans J. Wackers
通讯作者：
Frans J. Wackers
影响因子：
20.1
作者：
ABILDSKOV, JA
通讯作者：
ABILDSKOV, JA
心脏组织计算机模拟和组织实验中的动作电位碰撞
影响因子：
4.6
作者：
B. Steinhaus;K. Spitzer;S. Isomura
通讯作者：
S. Isomura