To assess, to control, to exclude: effects of biobehavioral factors on circulating inflammatory markers.
To assess, to control, to exclude: effects of biobehavioral factors on circulating inflammatory markers.
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DOI：
10.1016/j.bbi.2009.04.005
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发表时间：
2009-10
影响因子：
15.1
通讯作者：
Irwin, Michael R.
中科院分区：
文献类型：
--
作者：
O'Connor, Mary-Frances;Bower, Julie E.;Cho, Hyong Jin;Creswell, J. David;Dimitrov, Stoyan;Hamby, Mary E.;Hoyt, Michael A.;Martin, Jennifer L.;Robles, Theodore F.;Sloan, Erica K.;Thomas, KaMala S.;Irwin, Michael R.
行为科学家越来越多地将炎症生物学作为他们对疾病病理学的心理社会动力学研究的机制。然而，缺乏标准化的纳入和排除标准和相关控制变量的评估影响了这些研究的解释。本文回顾和讨论了人类生物行为因素，可以影响炎症循环标志物的测量。通过PubMed检索与炎症生物学和生物行为因素相关的关键词。年龄，性别和激素状态，社会经济地位，种族和种族，体重指数，运动，饮食，咖啡因，吸烟，酒精，睡眠中断，抗抑郁药，阿司匹林和心血管疾病的药物都进行了审查。提供了一套分层的建议，以确定是否应评估、控制或使用每个变量作为排除标准。这些建议提供了一个框架，观察和干预研究调查之间的联系，心理和行为因素和炎症。
Behavioral scientists have increasingly included inflammatory biology as mechanisms in their investigation of psychosocial dynamics on the pathobiology of disease. However, a lack of standardization of inclusion and exclusion criteria and assessment of relevant control variables impacts the interpretation of these studies. The present paper reviews and discusses human biobehavioral factors that can affect the measurement of circulating markers of inflammation. Keywords relevant to inflammatory biology and biobehavioral factors were searched through PubMed. Age, sex, and hormonal status, socioeconomic status, ethnicity and race, body mass index, exercise, diet, caffeine, smoking, alcohol, sleep disruption, antidepressants, aspirin, and medications for cardiovascular disease are all reviewed. A tiered set of recommendations as to whether each variable should be assessed, controlled for, or used as an exclusion criteria is provided. These recommendations provide a framework for observational and intervention studies investigating linkages between psychosocial and behavioral factors and inflammation.
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影响因子：
6.2
作者：
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