COVID-19 infection and nanomedicine applications for development of vaccines and therapeutics: An overview and future perspectives based on polymersomes.
COVID-19 infection and nanomedicine applications for development of vaccines and therapeutics: An overview and future perspectives based on polymersomes.
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COVID-19-19感染和纳米医学在开发疫苗和治疗剂中的应用：基于聚合物体的概述和未来观点。
DOI：
10.1016/j.ejphar.2021.173930
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发表时间：
2021-04-05
影响因子：
5
通讯作者：
Mohamud R
中科院分区：
文献类型：
--
作者：
Al-Hatamleh MAI;Hatmal MM;Alshaer W;Rahman ENSEA;Mohd-Zahid MH;Alhaj-Qasem DM;Yean CY;Alias IZ;Jaafar J;Ferji K;Six JL;Uskoković V;Yabu H;Mohamud R
2019年12月出现并引发2019年冠状病毒病(新冠肺炎)大流行的严重急性呼吸综合征冠状病毒2型(SARS-CoV-2)，以前所未有的突发公共卫生事件震惊世界。自这场大流行开始以来，科学家们做出了非凡的努力，以了解新冠肺炎的发病机制，并根据新的假设或过去的经验，通过提供各种预防、诊断和治疗机会来对抗这种感染。尽管取得了所有成就，但新冠肺炎仍然是一个日益严重的健康威胁，没有特别批准的疫苗或治疗方法。该综述重点介绍了新冠肺炎感染的最新进展，并特别强调了纳米药物的应用，这些应用有助于开发有效的新冠肺炎疫苗或治疗方法。本文就利用多聚纳米材料有效抑制细胞因子风暴，减轻新冠肺炎感染的严重程度，提出了一个新的发展前景。
The severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), which emerged in December 2019 and caused the coronavirus disease 2019 (COVID-19) pandemic, took the world by surprise with an unprecedented public health emergency. Since this pandemic began, extraordinary efforts have been made by scientists to understand the pathogenesis of COVID-19, and to fight the infection by providing various preventive, diagnostic and treatment opportunities based on either novel hypotheses or past experiences. Despite all the achievements, COVID-19 continues to be an accelerating health threat with no specifically approved vaccine or therapy. This review highlights the recent advances in COVID-19 infection, with a particular emphasis on nanomedicine applications that can help in the development of effective vaccines or therapeutics against COVID-19. A novel future perspective has been proposed in this review based on utilizing polymersome nano-objects for effectively suppressing the cytokine storm, which may reduce the severity of COVID-19 infection.
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DOI：
10.3390/ijerph13040430
发表时间：
2016-04-19
影响因子：
--
作者：
Chen YN;Hsueh YH;Hsieh CT;Tzou DY;Chang PL
通讯作者：
Chang PL
影响因子：
6.7
作者：
Ahmed, Mohamed K.;Afifi, Mohamed;Uskokovic, Vuk
通讯作者：
Uskokovic, Vuk
DOI：
10.3760/cma.j.issn.1001-0939.2020.0005
发表时间：
2020-02-06
期刊：
Zhonghua jie he he hu xi za zhi = Zhonghua jiehe he huxi zazhi = Chinese journal of tuberculosis and respiratory diseases
影响因子：
--
作者：
Chen, L;Liu, H G;Wei, S
通讯作者：
Wei, S
影响因子：
56.9
作者：
Discher, BM;Won, YY;Hammer, DA
通讯作者：
Hammer, DA
DOI：
10.1016/j.dsx.2020.04.020
发表时间：
2020-07-01
影响因子：
10
作者：
Astuti, Indwiani;Ysrafil
通讯作者：
Ysrafil