The alteration of gray matter volume and cognitive control in adolescents with internet gaming disorder.
The alteration of gray matter volume and cognitive control in adolescents with internet gaming disorder.
复制标题
患有网络游戏障碍的青少年灰质体积和认知控制的变化。
DOI：
10.3389/fnbeh.2015.00064
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发表时间：
2015
影响因子：
3
通讯作者：
Zhang M
中科院分区：
文献类型：
--
作者：
Wang H;Jin C;Yuan K;Shakir TM;Mao C;Niu X;Niu C;Guo L;Zhang M
目的：网络游戏障碍（IGD）已成为青少年中主要的行为障碍之一，已受到许多行为和神经影像学研究的关注。然而，很少有研究关注IGD青少年脑灰质体积（GMV）的改变与认知控制特征之间的关系。方法：28名IAD患者和28名年龄、性别匹配的健康对照者参与研究。采用优化的基于体素的形态学（VBM）技术研究了IGD青少年和健康对照者的脑形态学。采用Stroop任务测量IGD组认知控制表现，并对IGD组脑结构变化与行为表现进行相关性分析。结果：与健康对照组相比，IGD患者的双侧前扣带皮层（ACC）、楔前叶、辅助运动区（SMA）、顶叶上皮层、左背外侧前额叶皮层（DLPFC）、左脑岛和双侧小脑的GMV均下降。IGD组ACC的GMV与Stroop任务的不一致反应误差呈负相关。结论：我们的研究结果表明，青少年IGD患者GMV的改变与认知控制的表现改变有关，表明IGD引起了实质性的脑图像效应。
Objective: Internet gaming disorder (IGD) has been investigated by many behavioral and neuroimaging studies, for it has became one of the main behavior disorders among adolescents. However, few studies focused on the relationship between alteration of gray matter volume (GMV) and cognitive control feature in IGD adolescents. Methods: Twenty-eight participants with IAD and twenty-eight healthy age and gender matched controls participated in the study. Brain morphology of adolescents with IGD and healthy controls was investigated using an optimized voxel-based morphometry (VBM) technique. Cognitive control performances were measured by Stroop task, and correlation analysis was performed between brain structural change and behavioral performance in IGD group. Results: The results showed that GMV of the bilateral anterior cingulate cortex (ACC), precuneus, supplementary motor area (SMA), superior parietal cortex, left dorsal lateral prefrontal cortex (DLPFC), left insula, and bilateral cerebellum decreased in the IGD participants compared with healthy controls. Moreover, GMV of the ACC was negatively correlated with the incongruent response errors of Stroop task in IGD group. Conclusion: Our results suggest that the alteration of GMV is associated with the performance change of cognitive control in adolescents with IGD, which indicating substantial brain image effects induced by IGD.
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