Peripapillary choroidal thickness in healthy Chinese subjects.

Peripapillary choroidal thickness in healthy Chinese subjects.
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中国健康受试者的视乳头周围脉络膜厚度

DOI:
10.1186/1471-2415-13-23
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发表时间:
2013-06-10
期刊:
影响因子:
2
通讯作者:
Zhang X
Zhang X
中科院分区:
医学4区
文献类型:
--
作者:
Huang W;Wang W;Zhou M;Chen S;Gao X;Fan Q;Ding X;Zhang X

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[目的]评价中国健康人群眼底脉络膜厚度,并探讨其影响因素。健康志愿者76例(76只眼),均无眼部或全身症状。采用增强深度成像光谱域光学相干断层扫描技术对所有患者进行脉络膜扫描(360度、直径3.4 mm的乳头周围环扫描)。脉络膜厚度在颞部、颞上部、上鼻部、鼻部、鼻下部、下部和颞下部进行测量。平均乳头周围脉络膜厚度为165.03 ± 40.37μm,其中鼻下、下、颞上、颞上、鼻上、鼻侧厚度明显小于颞部、颞上部、上鼻部、颞部厚度(p < )。在下鼻腔、下鼻道和下颞骨厚度之间没有发现统计学意义上的差异。平均脉络膜厚度随年龄增长呈线性下降(β = −1.33,95%CI−1.98,-0.68,P < 0.001)。平均脉络膜厚度与其他因素(性别、屈光度、眼轴长度、平均视网膜神经纤维层厚度、眼压、舒张压、收缩压、平均血压、舒张压、收缩压、平均眼灌注压)之间无相关性。鼻下、下、颞下乳头周围脉络膜厚度明显小于颞部、颞上、上、鼻上和鼻部厚度。随着年龄的增长,乳头周围脉络膜变薄。
To evaluate the peripapillary choroidal thickness of a healthy Chinese population, and to determine its influencing factors. A total of 76 healthy volunteers (76 eyes) without ophthalmic or systemic symptoms were enrolled. Choroidal scans (360-degree 3.4 mm diameter peripapillary circle scans) were obtained for all eyes using enhanced depth imaging spectral-domain optical coherence tomography. Choroid thickness was measured at the temporal, superotemporal, superior, superonasal, nasal, inferonasal, inferior, and inferotemporal segments. The average peripapillary choroidal thicknesses were 165.03 ± 40.37 μm. Inferonasal, inferior, and inferotemporal thicknesses were significantly thinner than temporal, superotemporal, superior, superonasal, nasal thicknesses (p < 0.05). No statistically significant difference was found among inferonasal, inferior, and inferotemporal thicknesses. The average peripapillary choroidal thickness decreased linearly with age (β = −1.33, 95% CI −1.98, -0.68, P < 0.001). No correlation was noted between average choroidal thickness and other factors (gender, refractive error, axial length, average retinal nerve fiber layer thickness, intraocular pressure, diastolic blood pressure, systolic blood pressure, mean blood pressure, diastolic ocular perfusion pressure, systolic ocular perfusion pressure, and mean ocular perfusion pressure). The inferonasal, inferior, inferotemporal peripapillary choroidal thicknesses were significantly thinner than temporal, superotemporal, superior, superonasal, and nasal thicknesses. A thinner peripapillary choroid is associated with increasing age.
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