Effect of low intensity pulsed ultrasound stimulation on sinus augmentation in rabbits.
Effect of low intensity pulsed ultrasound stimulation on sinus augmentation in rabbits.
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DOI：
10.1111/clr.12136
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发表时间：
2014-06
影响因子：
4.3
通讯作者：
Ochi M
中科院分区：
文献类型：
--
作者：
Takebe H;Nakanishi Y;Hirose Y;Ochi M
本研究的目的是评价低强度脉冲超声刺激(LIPUS)的效果，并利用兔模型确定促进鼻窦隆起术中骨再生的最佳频率。30只雄性兔行窦房结扩张术。两侧勾勒出两个矩形鼻骨窗。每天在实验部位以两种不同的频率(1 MHz和3 MHz)施加Lipus，持续2、4和8周。实验和对照部位的每个组织学区从顶区到深度为5 mm，分为上下两部分。测量每一新生骨面积。在2、4和8周时，1 MHz组实验部位上、下两个部位的新骨生长均明显多于对照部位。联合测量各部位上、下部时，1 MHz组在2、4、8周时测试部位与对照部位之间差异有统计学意义，而3 MHz组测试部位与对照部位之间无统计学差异。结果表明，LIPUS在临床上可促进新骨形成，1 MHz频率的LIPUS对新骨形成的促进作用大于3 MHz频率的LIPUS，直至术后8周。
The objective of the present study was to evaluate the efficacy of low intensity pulsed ultrasound stimulation (LIPUS) and to determine the optimal frequency for enhancing bone regeneration in sinus augmentation using a rabbit model. Thirty male rabbits underwent sinus augmentation. Two rectangular nasal bone windows were outlined bilaterally. LIPUS was applied at two different frequencies (1 MHz and 3 MHz) on experimental sites daily for 2, 4 and 8 weeks. Each histological area of the experimental and control sites was divided into upper and lower parts from the parietal region to a depth of 5 mm. Each area of new bone was measured. At 2, 4 and 8 weeks, the experimental sites in the 1 MHz group exhibited significantly more new bone growth than the control sites in both the upper and lower parts. When the upper and lower parts of each area were measured in combination there was a statistical difference between the test and control sites in the 1 MHz group at 2, 4 and 8 weeks; however, there were no statistical differences between the test and control sites in the 3 MHz group. The results suggest that clinical application of LIPUS for sinus augmentation may promote new bone formation, and that the effect of LIPUS for sinus augmentation at a frequency of 1 MHz was greater than at 3 MHz until 8 weeks after sinus augmentation.
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影响因子：
4.3
作者：
Yildirim, M;Spiekermann, H;Edelhoff, D
通讯作者：
Edelhoff, D
DOI：
10.1002/jbm.b.30989
发表时间：
2008-07-01
影响因子：
3.4
作者：
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通讯作者：
Pounder, Neill
DOI：
10.1111/j.1708-8208.2001.tb00127.x
发表时间：
2001-01-01
影响因子：
3.6
作者：
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通讯作者：
Rangert, B
影响因子：
2.9
作者：
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通讯作者：
Beziat, Jean-Luc
DOI：
10.1016/j.bjoms.2011.03.001
发表时间：
2012-04-01
影响因子：
1.8
作者：
Liu, Qing;Liu, Xin;Ding, Yuxiang
通讯作者：
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