Influence of health behaviours on the incidence of infection and allergy in adolescents: the AFINOS cross-sectional study.
Influence of health behaviours on the incidence of infection and allergy in adolescents: the AFINOS cross-sectional study.
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DOI：
10.1186/1471-2458-14-19
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发表时间：
2014-01-09
影响因子：
4.5
通讯作者：
Marcos A
中科院分区：
文献类型：
--
作者：
Nova E;Martínez-Gómez D;Gómez-Martínez S;Veses AM;Calle ME;Veiga OL;Marcos A
一些健康行为容易影响青少年过敏和/或常见感染的发生率；然而，这些情况可能发生的程度和方式大多是未知的。这项研究探讨了与身体活动、久坐、饮食和睡眠相关的健康行为与青少年过敏和感染症状的关系，以及与可能介导疾病发病率的生物标志物的关系。该研究共纳入了来自西班牙马德里地区的 2054 名青少年（50.7% 是女孩）。研究前三个月的感染和过敏症状的发生率是通过自填问卷获得的。身体和久坐活动、身高和体重、饮食习惯和睡眠时间也被自我报告，并通过逻辑回归分析评估它们对感染和过敏发生率的影响。在 198 名受试者的子样本中评估了血液生物标志物（IgE、嗜酸性粒细胞百分比、瘦素、白细胞介素 (IL)-2、IL-4、IL-5 和 IL-10）。充足的睡眠时间（OR = 0.79，95%CI：0.64至0.97）和不健康的体重状况（超重/肥胖）（OR = 1.35，95%CI：1.04-1.74）分别与过敏发生率的降低和增加独立相关。没有观察到与感染发生率显着相关。有和没有过敏症状的青少年之间的 IgE 和瘦素有所不同。在回归模型中，IgE 与睡眠时间不足显着相关，而瘦素则与体重状况显着相关。体重过重和睡眠时间不足与青少年过敏症状的发生率独立相关。青春期充足的睡眠时间和体重可能与降低过敏症状的风险有关。
Some health behaviours are liable to affect the incidence of allergies and/or common infections in young people; however, the extent and ways in which these might occur are mostly unknown. This study examines the association of health behaviours related to physical activity, sedentariness, diet and sleep with allergy and infection symptoms in adolescents, and also with biological markers that might mediate disease incidence. The study comprised a total of 2054 adolescents (50.7% girls) from the Madrid region of Spain. The incidence of infection and allergy symptoms three months prior to the study was obtained from a self-administered questionnaire. Physical and sedentary activities, height and weight, food habits and sleep duration were also self-reported and their influence on infection and allergy incidence was assessed by logistic regression analysis. Blood biomarkers (IgE, eosinophil percentage, leptin, interleukin (IL)-2, IL-4, IL-5 and IL-10) were evaluated in a subsample of 198 subjects. Adequate sleep duration (OR = 0.79, 95%CI: 0.64 to 0.97) and unhealthy weight status (overweight/obesity) (OR = 1.35, 95%CI: 1.04-1.74) were independently associated with decreased and increased allergy incidence, respectively. No significant association was observed with infection incidence. IgE and leptin differed between adolescents with and without allergy symptoms. In regression models IgE was significantly associated with inadequate sleep duration and leptin with weight status. Excess weight and inadequate sleep duration are independently associated with the incidence of allergy symptoms in adolescents. Adequate sleep duration and weight during adolescence might be relevant for a decreased risk of suffering allergy symptoms.
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DOI：
10.2174/1874306401105010031
发表时间：
2011
期刊：
The open respiratory medicine journal
影响因子：
--
作者：
Aldabal L;Bahammam AS
通讯作者：
Bahammam AS
影响因子：
6.1
作者：
Jarvis, D;Chinn, S;Burney, P
通讯作者：
Burney, P
影响因子：
2.3
作者：
Boyle, Julia;Eriksson, Malin;Kumagi, Yuji
通讯作者：
Kumagi, Yuji
影响因子：
4.7
作者：
Irei, AV;Takahashi, K;Yamamoto, S
通讯作者：
Yamamoto, S
影响因子：
4.4
作者：
Karisson, Erik A.;Sheridan, Patricia A.;Beck, Melinda A.
通讯作者：
Beck, Melinda A.