Heterocalixrenes (Chemistry)

这项研究得到了有机和宏观的支持， 分子化学计划。 利用的分子 生命系统已经进化了数十亿年 因此 卟啉和咕啉家族的结构对于 维生素B-12，细胞色素C-450， 血红蛋白和叶绿素等。 这项研究将 研究一种结构类型， 系统被模仿。 本研究将合成该化合物的吡啶类似物， 卟啉系统，其中吡咯环将被 系统地被吡啶基官能团取代。 这 将导致具有电子的四齿大环， 可怜的戒指，应该有许多新颖的电子和 配位性质 对应的属性 三齿系统也将被研究。 工作应该（1） 开发新的合成途径进入这些系统; 2）化学 修改“中间”桥梁; 3）物理研究 这些系统的性能;和4）金属的研究 复合物及其可能的堆叠相互作用。

This research is being supported by the Organic and Macro- molecular Chemistry Program. The molecules utilized by living systems have evolved over billions of years. Thus the porphyrin and corrin families of structures are crucial to the catalytic properties in vitamin B-12, cytochrome C-450, hemoglobin and chlorophyll among others. This research will look into a structural type which will permit some of these systems to be mimicked. This research will synthesize the pyridino analog of the porphyrin system in which the pyrrole rings will be systematically replaced by the pyridino functionality. This will result in quadridentate macrocycles possessing electron- poor rings which should have many novel electronic and coordination properties. The properties of the corresponding tridentate systems will also be examined. The work should 1) develop new synthetic paths into these systems; 2) chemical modification of the "meso" bridges; 3) studies of the physical properties of these systems; and 4) study of the metal complexes and their possible stacking interactions.