Spherical Hydrophilic Polymers: Synthesis, Characterization and Applications

本研究的主要主题是研究内部修饰的树状大分子（级联大分子）的制备、结构和化学性质。根据这一目标，设计和合成面向应用的树突状构建块，这些构建块具有屏蔽的或惰性的、可转换的功能，以便在树突状构建后使用。项目目标包括：1)构建功能差异化的树突构建块，将面向应用的功能结合到特定地点的树突中。2)构建具有可与其他树状大分子形成连接的区隔化部分的树状大分子。3)协同（“组合”）构建多个树突组件（树突库）。4)单分子胶束约束和模板法制备单分散、小颗粒的半导体晶体（也称为“量子点”）。5)将半导体晶体精确排列成三维超阵列，实现q -粒子电子耦合“微调”。这项研究的优点依赖于对高度分支的、专门设计的大分子的物理化学性质的化学研究，以及这些性质中固有的随之而来的效用。这项研究的结果将为理解在“设计”反应环境中发生的化学现象奠定基础。＊＊＊

9622609 Newkome The overriding theme of this research concerns the investigation of the preparation, structural aspects, and chemical properties of dendrimers (cascade macromolecules) that have been internally modified. Pursuant to this goal is the design and synthesis of application-oriented dendritic building blocks possessing masked, or inert, transformable functionality to be accessed for use after dendrimer construction. Project goals include: 1) Construction of functionally differentiated dendritic building blocks for the site-specific incorporation of application-oriented functionality into dendrimers. 2) Construction of dendrimers with compartmentalized moieties capable of forming connections with other dendrimers. 3) Concommitant (`combinatorial") construction of multiple, dendritic assemblies (dendritic libraries). 4) Unimolecular micellar constrained and templated preparation of monodisperse, small particle, semiconductor crystallites (also described as "quantum dots"). 5) Precise arrangement of semiconductor crystallites into three-dimensional superarrays allowing Q-particle electronic coupling "fine tuning". %%% The merits of this research rely on the study of the chemistry associated with physicochemical properties of highly branched, specifically designed, macromolecules, and the attendant utility inherent in those properties. Results of this research will expand foundations for understanding of chemical phenomena occurring within "designer" reaction environments. ***