Spherical Hydrophilic Polymers: Synthesis, Characterization, and Applications

球形亲水聚合物：合成、表征和应用

• 批准号: 9217331
• 负责人: George Newkome
• 金额: $ 31.5万
• 依托单位: University of South Florida
• 依托单位国家: 美国
• 项目类别: Continuing Grant
• 财政年份: 1993
• 资助国家: 美国
• 起止时间: 1993-03-01 至 1997-02-28
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=9217331&HistoricalAwards=false
• 关键词: Spherical; Hydrophilic; Polymers; Synthesis; Characterization

Based on the 'void volume' incorporated into the infrastructure of pre-dense packed, dendritic macromolecules, a series of novel polymers will be constructed that possess internal, specifically located, metal, metalloid, and/or heterocyclic moieties. The proposed research will emphasize the synthesis and characterization of water-soluble cascade polymers with easily functionalized lipophilic interiors. These transformations will focus on the potential to manipulate internal reactive sites, at each generation, after cascade superstructure construction. Modification of the interior of these unimolecular micelles will allow preparation of metallospheres which are specifically designed, water-soluble catalysts. Characterization of these macromolecules will be accomplished via the standard techniques of NMR spectroscopy, electron microscopy, light-scattering, fluorescent-probe methods, solubility, osmotic pressure conductivity, and mass spectroscopy. The potential to perform chemistry within a micellar environment, inside a single molecule, will be investigated in detail. The use of these cascade polymers as solubilizing agents, microencapsulating agents, and host- transport agents will be continued. This research deals with the synthesis and properties of a new class of large spherical molecules. Because they are designed to have voids in their structure, it will be possible to incorporate various types of functional materials within these new structures. Their potential in various applications will be investigated.

基于预致密堆积的树枝状大分子的“空隙体积”，将构建一系列具有内部、特定位置的金属、类金属和/或杂环部分的新型聚合物。拟议的研究将侧重于具有易于官能化的亲油内层的水溶级联聚合物的合成和表征。这些转变将集中于在层叠的上层建筑建造后的每一代人中操纵内部反应部位的潜力。通过对这些单分子胶束内部的修饰，可以制备出专门设计的水溶性催化剂的金属球体。这些大分子的表征将通过核磁共振光谱、电子显微镜、光散射、荧光探针法、溶解度、渗透压传导性和质谱学等标准技术来完成。将详细研究在胶束环境中、在单个分子内执行化学操作的可能性。这些级联聚合物将继续用作增溶剂、微胶囊剂和宿主传输剂。本研究主要研究一类新型球形大分子的合成和性质。因为它们被设计成在其结构中有空隙，所以有可能在这些新结构中结合各种类型的功能材料。我们将研究它们在各种应用中的潜力。