Flow Cytometer for Biochemical and Biomedical Engineering Research

这是一份收购流式细胞仪的仪器方案。该仪器的一个独特特点是能够在单个细胞水平上测量细胞参数。这是通过将单个文件中的单元通过流室来实现的。根据仪器安装的传感设备的类型，可以测量各种类型的蜂窝组件。该仪器将由赖斯大学化学工程系的四个研究小组共享，其中包括与赖斯大学生物化学研究人员的互动，以及德克萨斯医学中心的几个细胞生物学小组。所涉及的研究课题包括：-免疫系统动力学-重组群体中宿主/质粒相互作用的研究--对哺乳动物细胞胞内代谢的影响--白细胞受体的调节内皮细胞相互作用.毛状根培养中群体异质性的特征

This is an instrumentation proposal for the acquisition of a flow cytometer. A unique characteristic of this instrument is its capability to measure cellular parameters at a single cell level. This is achieved by passing the cells in a single file through a flow chamber. Depending on the types of sensing devices that are installed with the instrument, various kinds of cellular components can be measured. The instrument will be shared by four research groups within the Department of Chemical Engineering at Rice University and includes interactions with investigators in Biochemistry at Rice, and several groups in cell biology at the Texas Medical Center. The research topics involved include: - Dynamics of immune systems - Study of host/plasmid interactions in recombinant populations - Stess effects on intracellular metabolism of mammalian cells - Receptor mediation of leukocyte/endothelial cell interactions - Characterization of population heterogeneity inhairy root cultures