A Teacher Enhancement Program to Stimulate Laboratory-based Instruction in DNA Science for Advanced Placement and Honors Biology Classes

一项教师培训计划，旨在促进DNA科学的实验室教学，用于高级进修和生物荣誉课程这项提议是为了支持分子遗传学研讨会1990~1992年暑期288名生物进修/荣誉教师调查分析DNA科学讲习班仿照成功的分子克隆课程(TEI87-51248)，将冷泉港实验室传统的研究生培训任务扩展到二级。在为期一周的研讨会上，老师们使用DNA限制性内切酶连接、琼脂糖凝胶电泳、微生物培养、细菌转化和质粒分离等技术，制作和分析重组DNA分子。周末的后续研讨会强化了学习经验，并强调了实施实验教学计划的实际方面。目前由NSF赞助的项目已经覆盖了12个州的449名生物教师，加州、北卡罗来纳州和威斯康星州的项目得到了资助。统计分析记录了研讨会参与者的显著行为影响，包括实验室教学、领导力网络和筹款活动，这些活动超过了NSF的资金支出。NSF的支持被高度利用，形成了可以说是美国所有机构对公共生物技术教育的最大承诺的基础。投资促进机构现在提议每年暑假举办四次讲习班，培训东南部和中西部的额外288名高中教师。每年夏天，三个“通勤者”研讨会将服务于大城市地区，而“住宅”研讨会将针对来自更广泛地理区域的少数族裔教师。我们还要求提供资金，以继续在24个州的1600名教师中对创新进行实质性的纵向研究，这些教师到目前为止已经教授了DNA科学课程。一笔相当于国家科学基金奖励14.5%的金额将作为费用分摊提供。

A Teacher Enhancement Program to Stimulate Laboratory-Based Instruction on DNA Science for Advanced Placement and Honors Biology Classes This proposal is to support workshops on molecular genetic analysis for 288 advanced placement/honors biology teachers during summers 1990-92. Modeled after the successful Molecular Cloning course, (TEI 87-51248), the DNA Science workshop extends the traditional postgraduate training mission of Cold Spring Harbor Laboratory to the secondary level. During the week-long workshops, teachers make and analyze a recombinant DNA molecule, using the techniques of DNA restriction and ligation, agarose gel electrophoresis, microbial culture, bacterial transformation, and plasmid isolation. A weekend follow-up workshop reinforces the learning experience and stresses the practical aspects of implementing a lab-teaching program. The current NSF-sponsored program has reached 449 biology teachers in 12 states-aided programs in California, North Carolina, and Wisconsin. Statistical analysis has documented significant behavioral effects among workshop participants, including lab teaching, leadership networking, and fundraising activities that more than match NSF funds expended. NSF support has been highly leveraged, forming the basis of what is arguably the largest commitment to public biotechnology education by any institution in the country. The PIs now propose to hold four workshops per summer that would reach an additional 288 high school teachers in the southeast and midwest. Three "commuter" workshops each summer would service large urban areas, while on "residential" workshop would target minority teachers from a wider geographic region. We also request funding to continue a substantial longitudinal study of innovation among the 1,600 teachers in 24 states who have been taught the DNA science curriculum to date. An amount equivalent to 14.5% of the NSF award is being contributed as cost-sharing.