A Comprehensive Database of Nucleic Acid Structure

为了理解核酸的性质和蛋白质识别它们的机制，理解精细结构的细节并结合序列和结构数据是必不可少的。我们的目标是开发一个核酸结构和结构特征的数据库，以便允许计算机查询结构特征、结构之间的特征相关性和序列-结构关系。为了实现这一目标，关于核酸晶体结构的所有现有原始信息和计算信息都将汇编到一个关系数据库中。将创建的系统将是便携的，许多计算机环境中的化学家和生物学家都可以访问。

In order to understand the properties of nucleic acids and the mechanisms by which they are recognized by proteins, it is essential to understand the details of fine structure and couple the sequence and structure data. Our goal is to develop a database of nucleic acid structures and structural features so as to allow computer queries about structural characteristics, correlations of features among structures, and sequence-structure relationships. The achieve this goal, all of the available primary and calculated information about crystal structures of nucleic acids will be assembled into a relational database. The system that will be created will be portable and accessible to chemists and biologists in a large number of computer environments.