Acqusition of a Raman Spectrometer

化学研究仪器计划的这个奖项 将帮助西方学院的化学系 获得具有激光和可变波长的拉曼光谱仪， 用于以下研究的温度能力 项目： 1. 机械作用和结构的确定 亲电芳香过程中存在的各种配合物 烷基化、氯化和酰化相关反应; 2. 金属离子结合对二级结构的影响 钙调素和其他调节蛋白; 3. 呋喃香豆素的光化学反应性 不饱和化合物，如DNA中的胸腺嘧啶残基; 4. 光化学反应性的机理研究 用激光诱导光CIDNP技术对黄素类化合物进行了研究。 5. 过渡金属配合物的合成 含有碳-碳三键。 拉曼光谱涉及振动和转动 分子的转变。 有时获得的信息 补充了从红外研究中获得的结果，并提供了 有价值的结构信息。 傅里叶变换拉曼 具有近红外激发的光谱提供了强大的 高背景荧光或样品问题解决方案 光降解或光降解性和增强的信噪比 质量. 拉曼光谱学是一种非常宝贵的研究工具 凝聚相化学和生物分子系统。

This award from the Chemistry Research Instrumentation Program will help the Department of Chemistry at Occidental College to acquire a Raman spectrometer with laser and variable temperature capability for use in the following research projects: 1. The determination of the mechanistic role and structure of various complexes present during electrophilic aromatic alkylation, chlorination and acylation-related reactions; 2. The effects of metal-ion binding on the secondary structure of calmodulin and other regulating proteins; 3. The photochemical reactivity of furocoumarins (psoralens) toward unsaturated compounds, such as thymine residues in DNA; 4. A mechanistic study of the photochemical reactivity of flavins by laser-induced photo-CIDNP technique. 5. The synthesis of bimetallic transition-metal complexes containing carbon-carbon triple bonds. Raman Spectroscopy is concerned with vibrational and rotational transitions in molecules. The information obtained sometimes complements that obtained from an infrared study and provides valuable structural information. Fourier-transform Raman spectroscopy with near-infrared excitation provides a powerful solution to problems of high background fluorescene or sample photodegradation or photolability and enhanced signal-to-noise quality. Raman spectroscopy is an invaluable tool in studies of condensed-phase chemical and biomolecular systems.