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"A Self Assembling Nanometer Tinker Toy From Phage T4 Tail Fiber Parts".

"A Self Assembling Nanometer Tinker Toy From Phage T4 Tail Fiber Parts".
“噬菌体 T4 尾部纤维部件的自组装纳米修补玩具”。
批准号:
9308834
负责人:
Edward Goldberg
金额:
$4.95万
依托单位:
依托单位国家:
美国
项目类别:
Standard Grant
财政年份:
1993
资助国家:
美国
项目状态:
已结题
起止时间:
1993-05-15 至 1995-06-30

项目摘要

项目成果

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中文摘要
翻译
这个探索性研究项目的小额拨款是使用细菌病毒T4的尾部纤维部分来检查这些蛋白质类建筑材料的机械和其他性能,其中许多似乎表现出不同寻常的强度和硬度。二聚体片段的产生数量适中,可用于结构分析。这些材料的结构信息将被用来促进分子建模和性能的理论估计,如刚性、弹性和拉伸强度,以及设计新的结构部件。通过使用基因技术改变基本构建块的末端,将制造出更长的聚合物。聚合物的平均长度可以通过添加不同极限浓度的“停止”亚基来确定。这项研究有可能从生物制品中生产出新的材料。
英文摘要
This small grant for exploratory research project is using tail fiber parts from the bacterial virus T4 to examine the mechanical and other properties of these proteinaceous building materials, many of which seem to exhibit unusual strength and stiffness. Dimer fragments are being produced in quantities appropriate for structural analysis. The structural information from these materials will be used to facilitate molecular modelling and theoretical estimations of properties such as stiffness, elasticity and tensile strength, as well as in designing novel structural parts. Longer polymers will be made by using genetic techniques to alter the ends of the basic building blocks. Average length of the polymers can be determined by adding "stop" subunits in different limiting concentrations. %%% This research has the potential to produce novel materials from biological products.
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会议论文
SGER: Controlled Self-Assembly of a Nanotriangle
  • 批准号:
    0124784
  • 项目类别:
    Standard Grant
  • 资助金额:
    $10.0万
  • 财政年份:
    2001
  • 负责人:
    Edward Goldberg
  • 依托单位:
Biomimetic Carpentry of Self-Assembling Functional Protein Nanostructures Based on Phage Tail Fibers
  • 批准号:
    9834603
  • 项目类别:
    Continuing Grant
  • 资助金额:
    $46.73万
  • 财政年份:
    1998
  • 负责人:
    Edward Goldberg
  • 依托单位:
The Role and Mechanism of Gene 12 Product in the T4 Phage Infection Process
  • 批准号:
    9006253
  • 项目类别:
    Continuing Grant
  • 资助金额:
    $21.98万
  • 财政年份:
    1990
  • 负责人:
    Edward Goldberg
  • 依托单位:
Comparative Marine Chemistries of Rhenium, Platinum Group Metals and Their Periodic Table Neighbors
海外基金