Colloidal Semiconductors for Macromolecular Recognition, Open Framework Structures, and Nonlinear Optical Applications

这个奖项是墨菲博士的启动补助金增量 化学博士后研究奖学金。研究 论述了胶体半导体的合成及其 应用于DNA分子识别，开放框架 结构和可调谐非线性光学材料。在 分子识别研究，胶体CdS和CdSe将是 用作球状蛋白质组蛋白的无机模拟物 DNA链是如何包裹自己的发光 半导体芯在辐照时的光谱将 深入了解DNA包裹的性质和机制 以及伴随DNA复制而产生的 转录。CdS和CdSe的空心球，其可以 显示不寻常的光致发光，也将准备和 嵌入在聚合物膜和溶胶-凝胶玻璃中。这些材料 对于非线性光学应用应该是有吸引力的。以来 CdS和CdSe发光对表面敏感 吸附物，非线性光学性质可以调谐， 分子在包封的胶体上的吸附。 %%% 量子尺寸的胶体半导体具有尺寸和表面 这些特性有助于各种诊断和 光学应用的学术和技术意义。

This award is the starter grant increment of Dr. Murphy's Postdoctoral Research Fellowship in Chemistry. The research deals with the synthesis of colloidal semiconductors and their application to molecular recognition by DNA, open framework structures and tuneable nonlinear optical materials. In the molecular recognition studies, colloidal CdS and CdSe will be used as an inorganic mimic of the globular protein histones about which DNA strands wrap themselves. The luminescence spectrum of the semiconductor cores upon irradiation will provide insights into the nature and mechanism of DNA wrapping and unraveling that accompanies DNA replication and transcription. Hollow spheres of CdS and CdSe, which may exhibit unusual photoluminescence, will also be prepared and embedded in polymer films and sol-gel glasses. These materials should be attractive for nonlinear optical applications. Since the luminescence of CdS and CdSe is sensitive to surface adsorbates, nonlinear optical properties can be tuned by adsorption of molecules on the encapsulated colloids. %%% Quantum-sized colloidal semiconductors have size and surface properties which lend themselves to a variety of diagnostic and optical applications of academic and technological significance.