Mass Spectrometry In Undergraduate Teaching Laboratories

质量谱计的使用正在整合到本科教学实验室中。惠普MS引擎有一个现代化的数据系统，能够真正的多任务处理和四台附加的个人电脑，允许大量学生接触实用的现代质谱分析。从大二到大四，接触和“动手”使用乐器的程度增加了。学生最初接触仪器是在有机实验室，学生在那里识别简单合成反应的产物。在物理化学中，通过离子-分子反应研究键形成的概念和反应机理。在无机实验室，学生们通常使用该仪器分析他们的无机合成产物，而在分析实验室，正在对全州收集的水和土壤样品进行氯代烃和多氯联苯的定量分析。最后，学生们在一些本科研究项目中使用质谱仪。精心选择实验，有效利用仪器时间，通过多台计算机轻松访问数据，使我们能够让大量学生接触实际的“动手”质谱分析。回顾文献表明，在本科水平的教学质谱明显不足。这个项目为纠正这个问题提供了一个模型。＊＊＊

9350846 Illies The use of a massspectrometer is being integrated into undergraduate teaching laboratories. The Hewlett-Packard MS Engine has a modern data system capable of true multi-tasking and four attached personal computers allowing exposure of large numbers of students to practical modern mass spectrometry. The degree of exposure and "hands on" use of the instrument increases from the sophomore to the senior level. Initial student contact with the instrument is in the organic laboratory where students are identifying the products of simple synthetic reactions. In physical chemistry, the concepts of bond formation and reaction mechanisms are being studied through ion-molecule reactions. In the inorganic labs, students routinely are using the instrument to analyze the products of their inorganic syntheses, while in the analytical laboratories, quantitative analysis of chlorinated hydrocarbons and polychlorinated biphenyls is being carried out on water and soil samples collected throughout the state. Finally, students are using the mass spectrometer in a number of undergraduate research projects. Careful choice of experiments, efficient use of instrument time, and easy data access through multiple computers are enabling us to expose large numbers of students to practical "hands on" mass spectrometry. A review of the literature shows a marked deficiency in teaching mass spectrometry at the undergraduate level. This project is providing a model for correcting that problem. ***