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Retrovirus silencing and chromatin reorganization in stem cells

Retrovirus silencing and chromatin reorganization in stem cells
干细胞中的逆转录病毒沉默和染色质重组
批准号:
210652
负责人:
Ellis James R
金额:
$25.88万
依托单位国家:
加拿大
项目类别:
Operating Grants
财政年份:
2010
资助国家:
加拿大
项目状态:
已结题
起止时间:
2010-09-01 至 2013-09-01

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中文摘要
翻译
诱导多能干细胞(iPS)是通过诱导皮肤细胞在培养中转变为干细胞而产生的。这种细胞诱导被称为“重编程”,是通过使用病毒传递四种基因的组合来完成的,这些基因通常控制细胞的生长。
英文摘要
Induced Pluripotent Stem (iPS) cells are generated by inducing skin cells to change into stem cells in culture. This cell induction is called "reprogramming" and is performed by using viruses to deliver a combination of four genes that normally control th
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Canada Research Chair - Tier 1
  • 批准号:
    454005
  • 项目类别:
  • 资助金额:
    $101.99万
  • 财政年份:
    2021
  • 负责人:
    Ellis James R
  • 依托单位:
Post-transcriptional regulation of functionally significant gene sets during neurodevelopment of Rett syndrome
  • 批准号:
    409282
  • 项目类别:
    Operating Grants
  • 资助金额:
    $66.6万
  • 财政年份:
    2019
  • 负责人:
    Ellis James R
  • 依托单位:
Identification of converging Molecular Pathways Across Chromatinopathies as Targets for Therapy: IMPACT
  • 批准号:
    387180
  • 项目类别:
    Operating Grants
  • 资助金额:
    $27.32万
  • 财政年份:
    2018
  • 负责人:
    Ellis James R
  • 依托单位:
Regulation of mRNA stability and translation during human neurodevelopment
  • 批准号:
    345198
  • 项目类别:
    Operating Grants
  • 资助金额:
    $41.77万
  • 财政年份:
    2016
  • 负责人:
    Ellis James R
  • 依托单位:
海外基金