International Postdoctoral Fellows Program: Development and Evolution of Crustacean Limbs

9407753 Williams该奖项是国际青年研究员和博士后研究员计划的一部分，该计划使美国科学家和工程师能够在国外公认的卓越研究中心进行三到十二个月的研究。该计划的奖励为联合研究提供了机会，并利用独特或互补的设施、专业知识和国外的实验条件。该奖项将支持Terri a . Williams博士对维也纳大学的Gerd B. Muller博士进行为期12个月的博士后研究访问，研究甲壳类动物四肢的发育和进化。肢体形态的发育与进化之间的关系主要是通过比较产生脊椎动物肢体的细胞机制和解剖图案分子在早期果蝇胚胎学中的作用来探索的。威廉姆斯博士建议通过研究甲壳类动物的肢体发育来连接这两种方法。我们对节肢动物肢体形成的细胞机制知之甚少。在果蝇身上发现的许多模式可能是一种经历了形式巨变的动物所特有的，在变形过程中，小袋上皮细胞发育成成年肢体。她将通过直接比较参与不同甲壳类肢体形态形成和增殖的细胞机制来寻找肢体发育的潜在主题。＊＊＊

9407753 Williams This award is under the International Junior Investigator and Postdoctoral Fellows Program, which enables U.S. scientists and engineers to conduct three to twelve months of research abroad at research centers of proven excellence. The program's awards provide opportunities for joint research, and the use of unique or complementary facilities, expertise and experimental conditions abroad. This award will support a twelve-month postdoctoral research visit by Dr. Terri A. Williams to work with Dr. Gerd B. Muller at the University of Vienna on the development and evolution of crustacean limbs. The relationship between the development and evolution of limb morphology has been explored mostly by comparing cellular mechanisms responsible for generating vertebrate limbs and by dissecting the role of patterning molecules in early Drosophila embryology. Dr. Williams proposes to bridge these two approaches by examining crustacean limb development. Little is known about the cellular mechanisms that form limbs in arthropods. Much of the patterning found in Drosophila may be unique to an animal that undergoes radical change in form and during metamorphosis develops adult limbs from small pockets of epithelial cells. She will look for underlying themes of limb development by directly comparing the cellular mechanisms involved in the formation and proliferation of different crustacean limb morphologies. ***