International Postdoctoral Fellows Program: Development and Evolution of Crustacean Limbs

威廉姆斯9407753 该奖项是根据国际初级研究员和博士后研究员计划，该计划使美国科学家和工程师能够在国外的卓越研究中心进行三到十二个月的研究。 该计划的奖项提供了联合研究的机会，以及使用国外独特或互补的设施，专业知识和实验条件。 该奖项将支持Terri A博士为期12个月的博士后研究访问。威廉姆斯与博士格尔德B。 穆勒在维也纳大学关于甲壳类动物四肢的发展和进化。 肢体形态的发育和进化之间的关系主要是通过比较负责产生脊椎动物肢体的细胞机制和解剖早期果蝇胚胎学中图案分子的作用来探索的。 威廉姆斯博士建议通过研究甲壳类动物的肢体发育来弥合这两种方法。 对节肢动物肢体形成的细胞机制知之甚少。 在果蝇中发现的许多模式可能是一种动物所独有的，这种动物在形态上发生了根本性的变化，在变态过程中，从上皮细胞的小口袋中发育成四肢。 她将通过直接比较不同甲壳类动物肢体形态形成和增殖的细胞机制来寻找肢体发育的潜在主题。 ***

9407753 Williams This award is under the International Junior Investigator and Postdoctoral Fellows Program, which enables U.S. scientists and engineers to conduct three to twelve months of research abroad at research centers of proven excellence. The program's awards provide opportunities for joint research, and the use of unique or complementary facilities, expertise and experimental conditions abroad. This award will support a twelve-month postdoctoral research visit by Dr. Terri A. Williams to work with Dr. Gerd B. Muller at the University of Vienna on the development and evolution of crustacean limbs. The relationship between the development and evolution of limb morphology has been explored mostly by comparing cellular mechanisms responsible for generating vertebrate limbs and by dissecting the role of patterning molecules in early Drosophila embryology. Dr. Williams proposes to bridge these two approaches by examining crustacean limb development. Little is known about the cellular mechanisms that form limbs in arthropods. Much of the patterning found in Drosophila may be unique to an animal that undergoes radical change in form and during metamorphosis develops adult limbs from small pockets of epithelial cells. She will look for underlying themes of limb development by directly comparing the cellular mechanisms involved in the formation and proliferation of different crustacean limb morphologies. ***