New Strategies for Enantioselective Cyclization Catalysis

在有机动力学项目的资助下，斯坦福大学的韦茅斯教授将开发新的催化和对映选择性方法，利用过渡金属化合物构建多环环。将继续进行各种取代碳环和杂环的对映选择性合成。在聚合物的催化对映选择性合成中开发的方法学将应用于小环的合成。利用过渡金属合成新型聚合物的方法将被应用于含碳环化合物的有效合成。所采用的技术适用于高效制造新型塑料、药品和未来社会需求所需的材料。

With funding from the Organic Dynamics Program Professor Waymouth of Stanford University will develop novel catalytic and enantioselective methods for the construction of polycyclic rings using transition metal compounds. The enantioselective synthesis of a variety of substituted carbocycles and heterocycles will be pursued. Methodology developed in the catalytic enantioselctive synthesis of polymers will be applied to the synthesis of small rings. Methods developed for the synthesis of novel polymers using transition metals will be applied to the efficient synthesis of carbon containing ring compounds. The techniques employed are applicable to the efficient manufacture of novel plastics, pharmaceuticals, and materials that will be necessary for future needs of society.