Acquisition of a 300 MHz NMR Instrument

本方案是用布鲁克公司生产的AMX 300MHz核磁共振仪部分替换用于液体和固体的令人兴奋的MSL 300MHz核磁共振仪。现有仪器的磁铁、前置放大器和大功率放大器将被保留，而控制台、计算机和磁盘驱动器将被更换。此外，将获得新的探头。MSL300仪器虽然对该大学正在进行的许多研究项目至关重要，但由于频繁需要维修和更换零件，维护成本已经达到了令人望而却步的地步。此外，获得合适的零件本身也变得越来越困难。最后，制造商不为这种类型的仪器提供新的软件，因为它为较新的型号。目前正在进行的主要研究领域包括材料合成，重分子（特别是煤和石油残渣，单独或共同处理方案）的处理，以及催化，包括催化剂的表征。核磁共振分析在材料、产物和催化剂的结构研究、机理测定、反应动力学研究和各种工艺的开发中发挥着重要作用，是匹兹堡唯一具有MAS能力（即可以分析固体样品）的仪器。目前使用NMR的研究是由NSF、DOE、EPA、DOD和一些工业公司赞助的，包括Miles、Calgon和Westinghouse等当地公司。1994年，16名研究生在主要研究人员的监督下工作，在他们的研究中需要使用核磁共振仪器。除了支持他们的研究项目，独特的仪器，如MAS-NMR为研究生和本科生提供宝贵的培训经验。从1990年到现在，Co-PI一直担任e NMR设施的主管，负责维护、维修和用户调度。目前的核磁共振仪器每周至少使用六天，并向大学内外的研究人员提供。

ABSTRACT CTS-9413698 Eric Beckman This proposal is for the partial replacement of an exciting MSL 300MHz Nuclear Magnetic Resonance (NMR) instrument used for both liquids and solids, with an AMX 300MHz instrument manufactured by Bruker. The magnet, preamplifiers and high power amplifiers of the existing instrument will be retained, while the console, computer, and disk drives will be replaced. Further, new probeheads will be acquired. The MSL300 instrument while vital to many research programs ongoing at the University, has reached the point where maintenance costs have become prohibitively expensive because of the frequent need for repairs and replacement of parts. Further, obtaining the right parts has itself become increasingly difficult. Finally, the manufacturer does not provide new software for this type of instrument, as it does for newer models. The main areas of research currently underway involve materials synthesis, processing of heavy molecules (particularly coal and petroleum resid, individually or in co-processing schemes), and catalysis, including characterization of catalysts. The NMR analyses play an essential role in the structural studies of materials, products, and catalysts, in determinations of mechanism, in kinetic studies of reactions, and in the development of various processes, and is the only instrument with MAS capability (i.e. which can analyze solid samples) in Pittsburgh. Research which currently employs the NMR is sponsored by NSF, DOE, EPA, DOD, and a number of industrial concerns, including local companies such as Miles, Calgon, and Westinghouse. In 1994, sixteen graduate students, working under the supervision of the Principal Investigators on this proposal, need to use the NMR instrument in their research. In addition to supporting their research projects, unique instruments such as the MAS-NMR provide invaluable training experiences for graduate and undergraduate students. From 1990 to the present, the Co-PI has been the director of th e NMR facility, responsible for maintenance, repair, and user scheduling. The current NMR instrument is in use at least six days per week and is made available to researchers both within and from outside the University.