Acquisition of High Field Nuclear Magnetic Resonance Instrumentation

学术研究基础设施（ARI）计划的这一奖项将 协助加州大学化学系 滨江升级现有的500兆赫核磁共振。 该设备将增强 研究领域包括：（1）人类 红细胞，肽中的二硫键和肽的相互作用 与肝素（2）维生素D蛋白中维生素D的结构研究 复合物（3）非标准核酸结构的测定（4） 低垒氢键在酶中的作用研究 催化作用;（5）大分子的结构-功能关系 具有生物学意义的结构。 核磁共振（NMR）光谱是最强大的工具， 化学家用来阐明分子结构的仪器。 它用于识别未知物质，表征特定物质， 分子内原子的排列，并研究 溶液中分子间的相互作用 获得最新技术 核磁共振谱是化学家进行前沿研究的基础 research. 这些核磁共振研究的结果是有用的领域 例如聚合物、催化和生物学。

This award from the Academic Research Infrastructure (ARI) Program will assist the Department of Chemistry at the University of California Riverside upgrade the existing 500 MHz NMR. This equipment will enhance research in a number of areas including the following: (1) human erythrocytes, disulfide bonds in peptides and the interaction of peptides with heparin (2) structural studies of vitamin D in vitamin D-protein complexes (3) determination of non-standard nucleic acid structures (4) investigation of the roles played by low-barrier hydrogen bonds in enzyme catalysis, and (5) structure-function relationships for macromolecular structures of biological significance. Nuclear Magnetic Resonance (NMR) spectroscopy is the most powerful tool available to chemists for the elucidation of the structure of molecules. It is used to identify unknown substances, characterize specific arrangements of atoms within molecules, and to study the dynamics of interactions between molecules in solution. Access to state-of-the-art NMR spectrometry is essential to chemists who are carrying out frontier research. The results from these NMR studies are useful in the areas such as polymers, catalysis, and in biology.