This project investigates the influence of motor learning mediated by different sensory systems (purely auditory or purely visual) on the auditory or visual perception of movements, the crossmodal interactions and its neural processing (especially within
This project investigates the influence of motor learning mediated by different sensory systems (purely auditory or purely visual) on the auditory or visual perception of movements, the crossmodal interactions and its neural processing (especially within
批准号:
106701844
负责人:
Dr. Annerose Engel
金额:
$0.0万
依托单位国家:
德国
项目类别:
Research Fellowships
财政年份:
2008
资助国家:
德国
项目状态:
已结题
起止时间:
2007-12-31 至 2010-12-31
中文摘要
镜像神经元系统被认为是观察和动作表示之间直接匹配的神经基础,并被认为是调解动作和意图的理解。听觉领域似乎也有一个类似的系统,将听到的动作与相应的运动表征相匹配。然而,系统内的跨通道相互作用尚未得到系统的研究:听觉和视觉镜像系统共享相同的神经基质吗?如果人类通过观察学习一个动作,镜像系统会对同一动作的声音做出反应吗?拟议的研究项目旨在通过结合人类功能性磁共振成像(fMRI)和创新的重复抑制(RS)范式来研究这些问题,这些范式支持高空间分辨率,用于确定大脑活动的定位。要研究的动作将是手指在钢琴键盘上的动作序列,这将通过听旋律或观察手指动作在运动训练中学习。此外,功能和行为数据将与结构数据相关:将使用弥散加权成像(DWI)检查每名受试者的白色通路差异,以将获得的值与运动训练期间的差异性能参数和(运动)感知任务期间相关脑区的个体血流动力学反应相关。
英文摘要
The mirror-neuron system is assumed to be the neural basis for a direct matching between observation and motor representations of actions and is considered to mediate the understanding of actions and intentions. There seems to be a similar system for the auditory domain that matches a heard action to the according motor representation. However, the crossmodal interactions within the system have not yet been systematically investigated: Do the auditory and the visual mirror system share the same neural substrate? If humans learn one action by observation, does the mirror system respond to the sound of the same action? The proposed research project aims at investigating these questions by combining functional magnetic resonance imaging (fMRI) in humans and innovative repetition suppression (RS) paradigms that support a high spatial resolution for the localization of identified brain activity. The actions to be studied will be sequences of finger movements on a piano keyboard, which will be learned in a motor training either by listening to a melody or by observation of finger movements. Furthermore, functional as well as behavioural data will be related to structural data: Differences in white matter pathways in each single participant will be examined using diffusion weighted imaging (DWI), in order to correlate the obtained values to differential performance parameters during a motor training and individual hemodynamic responses in relevant brain areas during a (motor) perception task.
期刊论文(1)
专著(0)
科研奖励(0)
会议论文
DOI:
10.1016/j.neuroimage.2012.03.038
发表时间:
2012-11-01
期刊:
NEUROIMAGE
影响因子:
5.7
作者:
[Engel, Annerose, Bangert, Marc, Keysers, Christian]
通讯作者:
Keysers, Christian
海外基金