Kinetics and Mechanisms: Oxidation Mechanisms of Some Selected Sulfur Compounds

西弗吉尼亚大学化学系鲁本·西莫伊博士得到了化学部无机、生物无机和有机金属项目的支持，以研究硫化物的氧化机理。Simoyi博士将研究选定硫化物的氧化动力学和机理，包括硫脲、亚磺酸、磺酸、硫化物和二甲基硫化物。还将研究生物相关含硫化合物的氧化，包括牛磺酸、半胱氨酸、异乙醇酸、蛋氨酸和谷胱甘肽。最终目标是对涉及含硫化合物的化学振荡器进行更完整的描述，并了解这些化合物的图案形成和对称破坏分叉。将使用停流法和连续流法、弛豫谱、浊度法、EPR和核磁共振等技术。这些系统与理解环境污染中硫的减少过程有关，氨基酸研究可能为了解它们的生理重要性提供基本的见解。硫在元素周期表中是一种独特的元素，因为它可以在很大程度上以不同的氧化态(从-2到+6)出现，因此它与金属、非金属和有机化合物具有相当大的活性。这些特性导致了与硫氧化物相关的环境问题，硫氧化物本身就是可能导致酸雨的主要大气污染物。这些硫化物和其他硫化物的详细反应活性，特别是那些具有环境和生物意义的硫化物，还没有被很好地了解。该项目将有助于阐明观察到的这些硫化物的不同寻常的反应模式，从而有助于更广泛地了解它们在这些重要领域中的作用。

Dr. Reuben Simoyi, Department of Chemistry, West Virginia University, is supported by the Inorganic, Bioinorganic, and Organometallic Program of the Chemistry Division for studies of the oxidation mechanisms of sulfur compounds. Dr. Simoyi will study the kinetics and mechanisms of oxidation of selected sulfur compounds including thioureas, sulfinic acids, sulfonic acids, sulfide, and dimethyl sulfide. Oxidation of biologically relevant sulfur containing compounds including taurine, cysteine, isethionic acid, methionine and glutathione will also be investigated. The ultimate goal is a more complete description of chemical oscillators involving sulfur compounds, and an understanding of the pattern formation and symmetry-breaking bifurcations of these compounds. Techniques such as stopped and continuous flow methods, relaxation spectra, turbidimetry, EPR and NMR will be utilized. These systems are relevant to an understanding of sulfur abatement procedures in environmental pollution, and the amino acid studies may provide fundamental insights into their physiological importance. Sulfur is a unique element in the periodic table because it can occur in widely varying oxidation states (from -2 to +6), and it is thus quite reactive with metals, nonmetals and with organic compounds. These characteristics contribute to the environmental concerns associated with oxides of sulfur, which themselves are major atmospheric pollutants which can cause acid rain. The detailed reactivity of these and other sulfur compounds, especially those with environmental and biological significance, is not well understood. This project will help to elucidate the unusual reactivity patterns observed for these sulfur compounds, and will thus contribute to a broader understanding of their role in these important areas.