U.S.-Australia Cooperative Research: Molecular Genetic Analysis of Normal and Mutant Visual System Development Studied with 3-D Time Lapse Microscopy
U.S.-Australia Cooperative Research: Molecular Genetic Analysis of Normal and Mutant Visual System Development Studied with 3-D Time Lapse Microscopy
批准号:
9731607
负责人:
John Pollock
金额:
$4.45万
依托单位国家:
美国
项目类别:
Standard Grant
财政年份:
1998
资助国家:
美国
项目状态:
已结题
起止时间:
1998-04-15 至 2002-03-31
中文摘要
9731607波洛克这项由卡内基-梅隆大学生物科学系约翰·波洛克教授和墨尔本大学遗传系菲利普·巴特汉姆教授合作的研究项目,重点是对黑腹果蝇正常和突变视觉系统发育的分子遗传分析。美国和澳大利亚的研究人员及其实验室为这项研究带来了互补的专业知识:波洛克实验室的图像分析和组织培养,以及巴特汉姆实验室的分子和遗传专业知识。该研究计划涉及一项多方面的攻击,即在发育中的眼睛中,菱形基因座在细胞的逐渐招募和分化中所起的作用。这项研究将进一步了解眼睛是如何发育的,以及含片是如何影响嗅觉和味觉的发育的。它还将为在国际环境中培训年轻研究人员提供一个平台。
英文摘要
9731607 Pollock This cooperative research project between Professor John Pollock, Department of Biological Sciences, Carnegie-Mellon University, and Professor Philip Batterham, Department of Genetics, University of Melbourne, focuses on the molecular genetic analysis of normal and mutant visual system development of Drosophila melanogaster. The U.S. and Australian researchers and their laboratories bring complementary expertise to this study: image analysis and tissue culture in Pollock's laboratory, and molecular and genetic expertise in Batterham's laboratory. The research plan involves a multifaceted attack on the role of played by the lozenge locus in the progressive recruitment and differentiation of cells in the developing eye. This research should provide further understanding of how eyes develop and also how lozenge influences the development of smell and taste. It will also provide a platform for the training of young researchers in an international setting.
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