NSF/Alfred P. Sloan Foundation Postdoctoral Research Fellowship in Molecular Evolution for FY 1998

DBI-9803908艾米·L·丹顿这一行动为美国国家科学基金会/阿尔弗雷德·P·斯隆1998年分子进化博士后研究奖学金提供了资金。这些奖学金支持在有机体进化问题的框架内，在分子水平上对生物模式和过程进行理论、比较、计算和/或实验分析的研究。每个研究金资助一项研究和培训计划，该计划将在一个赞助实验室进行。该奖学金的研究和培训计划题为两种草本植物查尔酮合成酶基因的自然选择和其他进化过程的历史。本研究使用聚合理论来研究玉米和珍珠谷子查尔酮合成酶(CHS)基因座的进化。通过对CHS基因谱系的统计分析，正在评估有效种群规模、突变、重组和选择的相对重要性。这项研究的主要目标是检测选择的影响，并探索在植物主要生物合成途径中支配分子多样性的历史力量。

Abstract DBI-9803908 Amy L. Denton This action funds an NSF/Alfred P. Sloan Postdoctoral Research Fellowship in Molecular Evolution for 1998. These fellowships support studies involving the theoretical, comparative, computational, and/or experimental analyses of biological patterns and processes at the molecular level within the framework of organismic evolutionary questions. Each fellowship supports a research and training plan to be carried out in a sponsoring laboratory. The research and training plan for this fellowship is entitled the history of natural selection and other evolutionary processes in the chalcone synthase genes of two grass species. This study uses coalescent theory to examine evolution at the chalcone synthase (Chs) loci in maize and pearl millet. The relative importance of effective population size, mutation, recombination and selection is being evaluated through statistical analyses of Chs gene genealogies. The primary goal of the research is to detect the influence of selection and explore the historical forces that have governed molecular diversity in a major plant biosynthetic pathway.