NSF/Alfred P. Sloan Foundation Postdoctoral Research Fellowship in Molecular Evolution for FY 1998

chichi -hua Chiu申请1998年美国国家科学基金会/Alfred P. Sloan分子进化博士后研究基金。这些奖学金支持涉及生物进化变化和适应框架内分子水平生物模式和过程的理论、比较、计算和/或实验分析的研究。这些研究还包括利用分子数据来解决更广泛的进化问题。每个奖学金支持在赞助实验室进行的研究和培训计划。该奖学金的研究和培训计划题为Hoxa-11调控的演变和鳍-肢过渡。Hoxa-11基因参与了鱼类鳍和四足动物肢体的发育。通过Hoxa-11核苷酸序列比较和基因表达研究，分析了Hoxa-11调控的进化。这些研究将提供一些遗传因素的见解，负责鳍到肢体的转变。

Abstract DBI-9803921 Chi-hua Chiu This action funds an NSF/Alfred P. Sloan Postdoctoral Research Fellowship in Molecular Evolution for 1998. These fellowships support studies involving the theoretical, comparative, computational, and/or experimental analyses of biological patterns and processes at the molecular level within the framework of organismic evolutionary change and adaptation. These studies also include the use of molecular data to address broader evolutionary questions. Each fellowship supports a research and training plan to be carried out in a sponsoring laboratory. The research and training plan for this fellowship is entitled evolution of Hoxa-11 regulation and the fin-limb transition. The Hoxa-11 gene is involved in fish fin and tetrapod limb development. The evolution of Hoxa-11 regulation is being analyzed by Hoxa-11 nucleotide sequence comparisons and gene expression studies. These studies will provide insights into some of the genetic factors responsible for the fin to limb transition.