Activation of C-F Bonds by Aryl Carbocations

本研究的重点是研究溶液中C-F键的活化 使用碳阳离子中间体作为亲电氟化物提取剂。 其中氟化物在碳原子之间转移并且是可逆的系统， 将研究光谱表征的离子， （C-F-C）债券将被准备。 碳阳离子介导的活化 氯氟烃和全氟化碳中的C-F键也将被 考察 有机和高分子化学 该计划正在支持该部门的托马斯莱克特卡博士的研究 约翰霍普金斯大学的化学教授。 莱克特卡教授将专注于 他致力于开发获得选择性C-F键的方法 activation. 该项目对更好地生产具有潜在影响 多氟烃和全氟烃是重要的商业产品。

The focus of this research is to study C-F bond activation in solution using carbocation intermediates as electrophilic fluoride abstractors. Systems wherein fluoride shifts between carbon atoms and are reversible and spectroscopically characterizable will be studied and ions containing (C-F-C) bonds will be prepared. The carbocation mediated activation of C-F bonds in chlorofluorocarbons and perfluorocarbons will also be examined. With this award, the Organic and Macromolecular Chemistry Program is supporting the research of Dr. Thomas Lectka of the Department of Chemistry at Johns Hopkins University. Professor Lectka will focus his work on developing methods for achieving selective C-F bond activation. The project has potential impact for the better production of poly- and perfluorinated hydrocarbons, important commercial products.