Engineering of composite particles to enhance performance in respiratory drug delivery

哮喘和慢性肺病等呼吸系统疾病影响着超过580万澳大利亚人，常用的治疗方法是通过药物吸入。虽然广泛的药物作为干粉吸入器可商购获得，但这些系统的效率很差，大多数装置向肺部递送的药物少于20%。本项目将开发一种基于复合微粒的高效呼吸道给药新方法。该项目开发的技术将推动澳大利亚的研究与创新和制药行业的发展，并改善政府促进和保持良好健康的关键优先领域的医疗保健成果：“健康的生活开始”和“良好的老龄化”

Respiratory conditions such as asthma and chronic pulmonary disease affect in excess of 5.8 million Australians and the common method of treatment is via drug inhalation. Although a wide range of drugs are commercially available as dry powder inhalers the efficiency of these systems is poor, with most devices delivering less than 20% to the lung. This project will develop a new method of high-efficiency respiratory drug delivery based on composite particles. The technology developed from this project will advance Australia’s Research & Innovation and Pharmaceutical industry sector, and improve healthcare outcomes in the government’s key priority area of Promoting and maintaining good health: ‘A healthy start to life’ and ‘Ageing well’