Stereochemistry of Nanoscale Molecules

本项目探索纳米级分子的合成及其立体化学研究。三种纳米级分子形态将被研究：茎掌簇、缠绕网络、壳和表面。实验、理论和计算化学将对具有这些形态的纳米级分子进行阐释，新的合成路线将被开发出来，以合成所选择的化学结构，从而扩大和成熟纳米级分子设计领域。有了这个奖项，有机和大分子化学项目继续支持加州大学圣地亚哥分校的杰伊·西格尔教授的研究。西格尔教授和他的同事们正在探索新型有机物质的性质，这些物质可以弥合微观和宏观之间的差距。这些分子组合将遵循基于基本有机化学的理性和深思熟虑的设计原则，并且它们的性质将使用各种技术进行探索。有了这些知识，制造具有特定性质和用途的大分子的能力可能很快就会实现。

This project explores the synthesis of nanoscale molecules and the study of their stereochemistry. Three nanoscale molecular morphologies will be studied: stem-palmate clusters, entwined networks, and shells and surfaces. Experimental, theoretical and computational chemistry will brought to bear on the elucidation of nanoscale molecules with these morphologies, and new synthetic routes will be developed to synthesize chemical structures chosen to expand and mature the area of nanoscale molecular design.With this Award, the Organic and Macromolecular Chemistry Program continues support for the research of Professor Jay Siegel of the University of California - San Diego. Professor Siegel and co-workers are exploring the nature of new kinds of organic matter that bridge the gap between the microscopic and macroscopic. These molecular assemblies will be subject to rational and deliberate design principles based on fundamental organic chemistry, and their properties will be explored using a variety of techniques. With this knowledge, the ability to create very large molecules with specific properties and purposes may soon be realized.