Process Technology of the Nonaqueous Sol-Gel Synthesis of Metal Oxide Nanoparticles

今天，金属氧化物纳米颗粒被用于许多已建立的和新的应用。它们可以通过溶剂型方法制备，具有很高的可控性和重现性，例如非水溶胶-凝胶合成，这在过去几年已经被提出用于许多系统。然而，由于缺乏对这些方法的详细工艺相关知识，这些方法的工业应用受到了阻碍。工艺参数和颗粒性质之间的相互关系一般不为人所知，而且颗粒形成的机理和动力学也只对少数几个单一体系有所了解。本研究项目涉及非水相合成金属氧化物纳米粒子的系统过程研究，利用两个模型系统获得关于过程参数对粒子形成的影响的详细知识。因此，不仅研究了颗粒形成、成熟和团聚的分子机理，而且还研究了颗粒的形成、成熟和团聚。在项目的最后阶段，利用实验数据建立了一个基于人口平衡的模型，该模型可以预测一次粒子和二次粒子形成的过程，并反映过程参数的影响。

Metal oxide nanoparticles today are utilized for many established and novel applications. They can be fabricated in high control and reproducibility via solvent-based approaches such as the nonaqueous sol-gel synthesis, which has been presented for a number of systems in the last years. The industrial use of these methods however is retarded by a lack of detailed process-related knowledge for these methods. The interrelation between process parameters and the particle properties is not generally known, and also the mechanisms and kinetics of particle formation are only understood for a few single systems. This research project involves systematic process studies for the nonaqueous synthesis of metal oxide nanoparticles, utilizing two model systems to obtain detailed knowledge on the influence of the process parameters on particle formation. Thereby, not only the molecular mechanisms are investigated, but also the particle formation, ripening and agglomeration. In the last phase of the project, the experimental data are utilized for the generation of a model based on population balances that can predict the processes of primary and secondary particle formation and reflect the influence of the process parameters.