POWRE: In vitro and Cellular EPR Spin-trapping Characterization of Reactive Oxygen Species Produced by the Iron Complex of the Anticancer Drug, Mitoxantrone

化学部颁发的这个POWRE奖延长了凯尼恩学院的迷迭香马鲁萨克博士与马尼托巴大学的布赖恩哈西诺夫一起工作的休假。这一休假将使Marusak博士能够将她对心脏保护药物金属络合物的无机化学及其对生物分子的体外氧化的研究扩展到Hasinoff博士是主要专家的此类系统的体内研究。这也将使她获得细胞培养技术和电子顺磁共振在生物无机化学中的应用经验。Marusak博士将利用这些知识来加强她与生物系同事的研究合作，维持她与Hasinoff博士的合作，并加强她的生物无机化学教学。

This POWRE award by the Chemistry Division extends a sabbatical leave for Dr. Rosemary Marusak from Kenyon College to work with Brian Hasinoff at the University of Manitoba. This leave will permit Dr. Marusak to extend her research on the inorganic chemistry of metal complexes of cardioprotective drugs and their in vitro oxidation of biomolecules to in vivo studies of such systems for which Dr. Hasinoff is a leading expert. It will also allow her to gain experience in cell culture techniques and electron paramagnetic resonance applications in bioinorganic chemistry. Dr. Marusak will use this knowledge to strengthen her research collaboration with her faculty colleagues in the Biology Department, sustain her collaboration with Dr. Hasinoff and enhance her teaching of bioinorganic chemistry.