QSB: Quantitative Analysis and Studies of the Correlation Between mRNA and Protein Expression Profiles in E. coli

目的是开发一个有意义的数学描述翻译，这可以提供深入了解大肠杆菌中的mRNA-蛋白质表达关系。 所提出的努力的两个首要目标是：（i）基于翻译过程的数学模型的制定和计算分析，确定影响mRNA和蛋白质表达相关性的参数，以及（ii）使用在所提出的工作的实验组成部分中获得的信息对这些参数进行量化。

The aim is to develop a meaningful mathematical description of translation, which can provide insights into the mRNA-protein expression relationship in Escherichia coli. The two overarching objectives of the proposed efforts are: (i) the identification of the parameters that affect the correlation of mRNA and protein expression based on the formulation and computational analysis of mathematical models of the translation processes, and (ii) the quantification of these parameters using the information derived within the experimental component of the proposed work.