CAREER: Scanning Tunneling Microscopy as a Synthetic Tool: C-C Coupling of Haloaromatic Reactants on Copper Surfaces

在加州大学河滨分校路德维希·巴特尔斯教授的实验室进行的这项研究项目，使用扫描隧道显微镜方法作为有机合成的工具。这个由分析和表面化学计划支持的早期职业奖，致力于与表面结合的有机分子的定向合成。基于最近使用STM尖端从碘苯合成联苯的工作，巴特尔斯和他的同事将把这种方法扩展到具有多个基本单元的单个分子的合成。这种方法将允许合成完全符合所需构象的分子。该方法在特定构象手性分子合成中的应用也在计划之中。这个基础研究计划将为分子电子器件和其他纳米材料合成策略的发展提供必要的背景和理解。巴特尔斯教授还在开发一门以半导体加工为重点的课程，这门课程将在化学系教授，作为该职业奖的一部分。详细了解复杂有机分子的结构将导致在本职业奖中开展的工作。巴特尔斯教授和他的同事将使用STM来操纵单个分子，将各种功能耦合在一起，使分子具有所需的构象吸附在底物上。最初的工作将使用偶联反应，然后是更复杂的加成反应。作为该职业奖的一部分，将开设半导体加工课程。

This research project, in the laboratory of Professor Ludwig Bartels at the University of California-Riverside, uses scanning tunneling microscope methods as a tool in organic synthesis. This early Career award supported by the Analytical and Surface Chemistry Program, addresses the site directed synthesis of organic molecules bound to surfaces. Building on recent work that demonstrated the synthesis of biphenyl from iodobenzene using the STM tip, Bartels and his coworkers will extend this approach to the synthesis of individual molecules having multiple elementary units. This approach will allow the synthesis of molecules of exactly the desired conformation. Application of this approach to the synthesis of chiral molecules of specific conformation is planned as well. This basic research program will provide the background and understanding necessary for the development of molecular electronic devices and other nanomaterial synthesis strategies. Professor Bartels is also developing a course focussing on semiconductor processing that will be taught in the Chemistry Department as a part of this Career award.A detailed understanding of the construction of complex organic molecules will result from the work carried out in this Career award. Professor Bartels and his coworkers will use STM to manipulate individual molecules, coupling various functionalities to make molecules of the desired conformation adsorbed on a substrate. Coupling reactions will be used for the initial work, followed by more complex addition reactions. A semiconductor processing course will be developed as part of this Career award.