Chiral Porous Materials for Enantioselective Catalysis and Separations

该奖项由化学部门(MPS)的先进材料计划和化学运输系统部门(ENG)的动力学、催化和分子计划授予北卡罗来纳大学教堂山分校，旨在设计和合成基于聚合物-金属配位网络的多孔手性晶体和非晶体沸石材料。获得这一奖项后，林教授将以现成的2，2‘-二羟基-1，1’-联苯为原料，制备各种不同官能团和拓扑结构的对映体刚性和桥联配体。这些手性多孔材料将具有可定制的纳米尺寸的手性口袋和功能，可用于对映体选择性分离和催化的潜在应用。这些材料既具有多相催化剂的优点(包括催化剂易于分离和回收、高稳定性和易于操作)，也具有均相催化剂的优点(包括活性中心的均质性、高效率、重复性、选择性和可控性，以及温和的反应条件)。此外，该奖项还将为不同类型的学生提供材料化学培训。获得该奖项后，将从现成的化学品中合成具有可定制的纳米手性口袋和功能的多孔和非晶态沸石类材料，这些材料有望在手性药物和精细化学品的合成中的对映选择性分离和催化方面得到应用。此外，这些催化剂将兼有多相催化剂和均相催化剂的优点。

This joint award made to University of North Carolina Chapel Hill by the Advanced Materials Program in the Division of Chemistry (MPS) and the Kinetics, Catalysis and Molecular program in the Division of Chemical Transport System (ENG) is to design and synthesize porous chiral crystalline and non-crystalline zeolitic materials based on polymer-metal coordination networks. With this award, Professor Lin will prepare a variety of enantiopure rigid and bridging ligands with different functional groups and topologies from readily available 2,2'-dihydroxy-1,1'-binaphthalene. These chiral porous materials will have tailorable nanometer-sized chiral pockets and functionalities that can be exploited for potential applications in enantioselective separations and catalysis. These materials will have both the advantages offered by heterogeneous catalysts (including facile catalyst separation and recovery, high stability, and ease of handling), and those offered by their homogeneous counterparts (including homogeneity of active sites, high efficiency, reproducibility, selectivity, and controllability, and mild reaction conditions). In addition, training in materials chemistry will be provided to a diversity of students with this award. With this award, porous and non-crystalline zeolite like materials with tailorable nanometer-sized chiral pockets and functionalities will be synthesized from readily available chemicals, and these materials are expected to have applications in enantioselective separations and catalysis for the synthesis of chiral drugs and fine chemicals. In addition, these catalysts will have the advantages of both heterogeneous and homogeneous catalysts.