MRI: Acquisition of a Multi-User System for the Direct Excitation of Lanthanide (III) Luminescence for Biological, Inorganic, and Materials Chemistry

该奖项来自主要研究仪器（MRI）项目，纽约州立大学布法罗分校化学系将获得一个多用户激光系统，用于直接激发镧系元素（Ln） （III）发光，用于生物、无机和材料化学。该设备将加强以下领域的研究：a)蛋白质掺杂干凝胶；b) Ln（III）离子在室温离子液体中的溶剂化；c) Ln（III）多金属氧酸盐作为新材料的构建单元；d)基于螺旋-螺旋-螺旋dna结合基序的人工核酸酶；e) Ln（III）配合物催化剂；f) Ln（III）探针用于金属离子RNA相互作用。该仪器不仅将被布法罗大学的教师使用，还将被爱荷华大学和亨特学院的研究人员使用。这些研究将利用Ln（III）发光来研究材料和催化剂，探测蛋白质和核酸中的金属离子结合位点；因此，它们将在许多领域产生影响，包括材料化学和生物化学。

With this award from the Major Research Instrumentation (MRI) Program, the Department of Chemistry at SUNY-Buffalo will acquire a multi-user laser system for the direct excitation of lanthanide (Ln) (III) luminescence for biological, inorganic, and materials chemistry. This equipment will enhance research in the following areas: a) protein-doped xerogels; b) solvation of Ln(III) ions in room temperature ionic liquids; c) Ln(III) polyoxometalates as building blocks for new materials; d) de novo artificial nucleases basded on helix-turn-helix DNA-binding motifs; e) Ln(III) complex catalysts; and f) Ln(III) probes for metal ion RNA interactions. This instrumentation will be used not only by faculty at the University at Buffalo, but also researchers at the University of Iowa and Hunter College. These studies will use Ln(III) luminescence to study materials and catalysts and probe metal ion binding sites in proteins and nucleic acids; therefore, they will have an impact in numerous fields, including materials chemistry and biochemistry .