Vibrational, Orientational, and Conformational Dynamics of Molecules in Solution

麻省理工学院化学系的Andrei Tokmakoff教授和他的研究生同事将利用二维红外光谱（2D-IR）研究溶液中生物分子的振动取向和构象动力学，该奖项由化学学部实验物理化学项目资助。这项研究的最终目标是开发研究蛋白质结构和动力学的新工具。除了所支持的研究的更广泛的科学影响外，从事这些项目的研究生将获得先进激光技术的经验。Tokmakoff教授还在他的网站上维护着一个2D-IR数据交换中心，他的课程材料也可以通过麻省理工学院的开放式课程计划获得。

In this award, funded by the Experimental Physical Chemistry Program of the Chemistry Division, Prof. Andrei Tokmakoff of the Chemistry Department of the Massachusetts Institute of Technology and his graduate student colleagues will study the vibrational orientational and conformational dynamics of biomolecules in solution with two-dimensional infrared (2D-IR) spectroscopy. The ultimate goal of this research is to develop new tools with which to study protein structure and dynamics. Besides the broader scientific impacts of the research being supported, the research students working on these projects will gain experience with advanced laser techniques. Prof. Tokmakoff also maintains a clearinghouse of 2D-IR data on his website, and his course materials are made available through MIT's OpenCourseWare initiative.