Acquisition of a Core Microarray Printing and Analysis Center

该奖项用于资助一所本科院校购买一台微阵列扫描仪和一台“芯片实验室”RNA生物分析仪。这些仪器将为教职员工和学生提供进行基因组水平实验的能力，使他们能够量化少量RNA并扫描微阵列玻片。这些仪器将有助于生物化学-化学和生物学项目中的各种研究项目，包括(1)藻类适应低温过程中基因表达的变化，(2)利用分子数据研究深海喷口生物及其共生伙伴之间的进化关系，以及(3)水和沉积物污染对冬季比目鱼基因表达的影响。这些仪器的获得将显著增强学院的研究能力和学生培训。本科生参与了该项目所有高级人员的研究。该仪器还将用于培训生物技术、发育生物学、分子遗传学、分子系统学和植物生理学等课程的学生。

This award funds the acquisition of a microarray scanner and a "Lab on a Chip" RNA Bioanalyzer for an undergraduate college. The instruments will provide faculty and students with the ability to undertake genomics level experiments by giving them the ability to quantify small amounts of RNA and to scan microarray slides. The instruments will benefit a variety of research projects in the Biochemistry-Chemistry and Biology programs including (1) changes in gene expression during the adaptation of algae to low temperatures, (2) using molecular data to examine evolutionary relationships among deep sea vent organisms and their symbiotic partners, and (3) the effects of water and sediment pollution on gene expression in winter flounder. The acquisition of these instruments will significantly enhance the research capability and student training at the college. Undergraduates are involved in the research of all of the senior personnel in this project. The instrumentation will also be used to train students in classes such as Biotechnology, Developmental Biology, Molecular Genetics, Molecular Systematics, and Plant Physiology.