Targeting DNA with Dynamic Combinatorial Chemistry

分子与DNA的相互作用是药物设计、疾病诊断和环境的基础。DNA是控制遗传信息的分子。化学家通常在实验室里合成这些分子。我们将使用一种创新的新方法来生产与DNA相互作用的分子，这种方法同样快速和高效，并反映了自然用于制造天然产品的过程。这项研究可能导致新的治疗、诊断和应用程序的设计，这将使澳大利亚社区受益，并将为研究人员提供在生物技术和制药领域就业所需技能的出色培训。

The interaction of molecules with DNA, the molecule that controls genetic information, is fundamental to drug design, diagnosis of disease and the environment. Chemists usually synthesise these molecules in the laboratory. We will use an innovative new approach to producing molecules that interact with DNA, that as fast and efficient and mirrors the processes used by Nature to make natural products. This research may lead to the design of new therapeutics, diagnostics and applications that will benefit the Australian community, and will provide excellent training of researchers in skills required for employment in the biotechnology and pharmaceutical fields.