CRIF:MU/RUI: Acquisition of a 500-MHz Nuclear Magnetic Resonance Spectrometer at Boise State University

博伊西州立大学化学和生物化学系将从化学研究仪器和设施：多用户(CRIF：MU)计划中获得一台500 MHz核磁共振(核磁共振)光谱仪。该仪器将用于几个需要高场核磁共振的生物化学和材料相关项目，包括：1)通过2-D核磁共振阐明锥形螺多肽(螺毒素)的三维(3D)溶液结构，2)合成和表征氮杂环丁二烯的DNA结合性质，3)对温度、光照、pH或压力变化响应的聚合物的合成和表征，4)单核锌酶人碳酸酐酶的模拟，5)用于非挥发性存储器件的硫系材料的鉴定和表征，6)硅-硼-氮-碳材料的液态和固态核磁共振表征。核磁共振波谱是化学家用来解释分子结构的最有力的工具。它被用来识别未知物质，表征分子内原子的特定排列，并研究溶液中分子之间相互作用的动力学。对于正在进行前沿研究的化学家来说，获得最先进的核磁共振光谱仪是必不可少的。这些核磁共振研究的结果将对合成有机化学、生物化学和材料化学产生影响。

The Department of Chemistry and Biochemistry at Boise State University will acquire a 500 MHz nuclear magnetic resonance (NMR) spectrometer with this award from the Chemistry Research Instrumentation and Facilities: Multi User (CRIF:MU) program. The instrument will be employed in several biochemistry and materials related projects requiring high field NMR including: 1) elucidation of the three-dimensional (3D) solution structures of Cone snail peptides (conotoxins) via 2-D NMR, 2) synthesis and characterization the DNA binding properties of aziridinomitosenes, 3) synthesis and characterization of polymers responsive to changes in temperature, light levels, pH or pressure, 4) modeling of the mononuclear zinc enzyme human carbonic anhydrase, 5) identification and characterization of chalcogenide materials for use in non-volatile memory devices, and 6) liquid and solid state NMR characterization of silicon-boron-nitrogen-carbon materials.Nuclear Magnetic Resonance (NMR) spectroscopy is the most powerful tool available to chemists for the elucidation of the structure of molecules. It is used to identify unknown substances, to characterize specific arrangements of atoms within molecules, and to study the dynamics of interactions between molecules in solution. Access to state-of-the-art NMR spectrometers is essential to chemists who are carrying out frontier research. The results from these NMR studies will have an impact in synthetic organic chemistry, biochemistry and materials chemistry.