MRI: Aquisition of a Laser Scanning Microscope for Imaging of Eukaryotic Organisms for Research and Teaching

北卡罗莱纳州立大学（NCSU）获得了一笔拨款，用于购买共聚焦激光扫描显微镜（CLSM）进行研究和培训。新的CLSM对于揭示NCSU正在进行的细胞、生化和遗传研究的生物学相关性至关重要。校园内的clsm都无法提供高分辨率、高灵敏度、动态和固定标本成像，以监测和分析生物体内低水平多种荧光化合物的分布。新的CLSM将被安置在细胞分子成像设施（CMIF）中，这是一个大学范围内的设施，是成像培训和研究的焦点。由于缺乏最先进的CLSM，校园培训和推广受到限制。CLSM将对NCSU的本科生、研究生和研究生的培训以及附近学院参加NCSU生物技术成像课程的本科生产生直接和广泛的影响。此外，CLSM将被一群不同的pi使用，他们在指导本科生进行独立研究和参加夏季REU项目时提供榜样，这些项目涉及来自非研究型大学和少数民族大学的学生。CLSM也将在参观和实践活动中为未来的学生和当地学校的孩子们提供重点。例如，CMIF是？拓展你的视野？该项目旨在吸引北卡罗来纳州各地的七年级女孩从事科学、数学和工程方面的职业。因此，新的CLSM将极大地扩展NCSU的教学、推广和研究活动。

A grant has been awarded to North Carolina State University (NCSU) to acquire a confocal laser scanning microscope (CLSM) for research and training. The new CLSM is essential to reveal the biological relevance of ongoing cellular, biochemical and genetic studies at NCSU. None of the CLSMs on campus were capable of the high resolution, high sensitivity, dynamic and fixed-specimen imaging required to monitor and analyze the distribution of low levels of multiple fluorescent compounds in organisms. The new CLSM will be housed in the Cellular Molecular Imaging Facility (CMIF), a University-wide facility that is a focal point for imaging training and research.On-campus training and outreach was constrained by the lack of a state-of-the-art CLSM. The CLSM will have immediate and broad impacts on the training of undergraduates, graduates and post graduates at NCSU as well as undergraduates at near-by colleges who take the NCSU biotechnology imaging course. Furthermore, the CLSM will be used by a diverse group of PIs who provide role models as they mentor undergraduates in independent research and participate in summer REU programs involving students from non-research I and minority universities. The CLSM also will be highlighted during the tours and hands on activities for prospective students and local school children. For example, CMIF is a focal point of the ?Expanding your Horizon? program aimed at attracting 7th grade girls from around the State of North Carolina to a career in science, mathematics and engineering. Therefore, the new CLSM will greatly expand teaching, outreach and research activities at NCSU.