Molecular evolution of a model oligomeric enzyme from bacterial extremophiles

这项研究项目对国家的好处包括：深入了解海洋微生物的可持续性，这些微生物在澳大利亚多样化的生态系统中发挥着重要作用；前沿技术的开发和应用，包括世界上最大的生命科学研究超级计算机设施的高性能计算；以及对发现针对致病菌的新型抗生素（如金黄色葡萄球菌）产生影响的知识。该项目还将培训几名年轻的澳大利亚人，学习他们急需的技能，包括细菌学、生物物理学、酶学、分子生物学、分子建模、蛋白质化学和结构生物学。

The national benefits of this research program include insight into the sustainability of marine microorganisms that play an important role in Australia's diverse ecosystem, the development and applications of frontier technologies including high-performance computing on the world's largest supercomputer facility for life science research, and knowledge impacting on the discovery of novel antibiotics that target pathogenic bacteria, like Golden Staph. This program will also train several young Australians in highly sought after skills, including bacteriology, biophysics, enzymology, molecular biology, molecular modelling, protein chemistry and structural biology.