MRI: Acquisition of a Single Crystal X-ray Diffractometer

明尼苏达大学德卢斯分校的Viktor Nemykin教授和他的同事们将获得来自重大研究仪器(MRI)计划的这一奖项，他们将获得一台带有CCD探测器的单晶X射线衍射仪，用于化学研究，包括：1)双核稀土配合物的表征，2)新的β-羟基酯合成子等效物的研究，3)弓形虫抑制剂的结构活性研究，4)高价过渡金属芳烃配合物的研究，5)有机天然产物的结构分析，以及其他项目。除了明尼苏达大学德卢斯分校的用户可以使用之外，圣斯科拉斯蒂卡学院(明尼苏达州德卢斯)和威斯康星大学高级分校的研究人员也将在他们自己的研究项目中使用该仪器。单晶X射线结晶学技术可以准确和精确地确定分子的完整三维结构，包括键距离和角度，并提供关于分子相对于邻近分子的空间排列的准确信息。这些研究将在许多领域产生影响，从合成有机化学和无机化学到生物系统和材料研究。该仪器将是教学和研究不可或缺的一部分，并将为目前没有现代结晶学设施的美国地区(明尼苏达州北部和威斯康星州北部)的大学和学院服务。

With this award from the Major Research Instrumentation (MRI) program, Professor Viktor Nemykin and colleagues from the University of Minnesota - Duluth will acquire a single crystal X-ray diffractometer with a CCD detector for use in chemical research, including: 1) characterization of binuclear lanthanide complexes, 2) studies with a new beta-hydroxy ester synthon equivalent, 3) structure-activity studies of toxoplasma gondii inhibitors, 4) studies of high-valent transition metal arene complexes, 5) structural analysis of organic natural products, and other projects. Besides being available to users at the University of Minnesota -- Duluth, researchers at the College of St. Scholastica (Duluth, MN) and University of Wisconsin - Superior will also use the instrument for their own research projects.The technique of single-crystal X-ray crystallography allows accurate and precise determination of the full three dimensional structure of a molecule, including bond distances and angles, and it provides accurate information about the spatial arrangement of molecules relative to the neighboring molecules. These studies will have an impact in a number of areas ranging from synthetic organic and inorganic chemistry to systems of biological interest and materials research. This instrument will be an integral part of teaching as well as research, and will serve universities and colleges in a region of the country (northern Minnesota and northern Wisconsin) that do not currently have modern crystallography facilities.