Console Replacement for a 20-Year Old 400 MHz Open Access NMR Spectrometer

从化学研究仪器和设施奖：部门多用户仪器计划（CRIF：MU），教授雅各布W。来自爱荷华州州立大学化学系的Petrich和同事将升级一台400 MHz的NMR光谱仪。升级后的仪器将能够快速进行脉冲场梯度的2D测量和可靠的1D测量，并具有可变温度功能。该仪器将用于支持以下研究活动：1）含有一系列杂原子（包括硼、磷、氮、氟和硅）的有机金属化合物的制备; 2）合成方法及其在组合化学中的应用; 3）阐明结构定向电子诱导和转环作用在多环刘易斯碱和酸催化中的作用; 4）环境响应材料、传感器和催化; 5）绿色催化;以及6）定制碳水化合物合成。核磁共振（NMR）光谱是化学家可用于阐明分子结构的最强大工具之一。它用于识别未知物质，表征分子内原子的特定排列，并研究溶液中分子之间相互作用的动力学。对于从事前沿研究的化学家来说，使用最先进的NMR光谱仪是必不可少的。这些NMR研究的结果将对合成有机/无机化学、材料、环境和生物化学产生积极影响。该仪器将成为教学和研究的一个组成部分。

With this award from the Chemistry Research Instrumentation and Facilities: Departmental Multi-User Instrumentation program (CRIF:MU), Professor Jacob W. Petrich and colleagues from the Department of Chemistry at Iowa State University will upgrade a 400 MHz NMR spectrometer. The upgraded instrument will enable rapid 2D measurements with pulse field gradients and reliable 1D with increased sensitivity, and will have variable temperature capabilities. The instrument will be used to support research activities such: 1) preparation of organometallic compounds that contain a range of heteroatoms including boron, phosphorus, nitrogen, fluorine, and silicon; 2) synthetic methodologies and applications in combinatorial chemistry; 3) elucidation of the roles of structurally directed electron induction and transannulation in polycyclic Lewis base and acid catalysis; 4) environmentally responsive materials, sensors and catalysis; 5) green catalysis; and 6) custom carbohydrate synthesis.Nuclear Magnetic Resonance (NMR) spectroscopy is one of the most powerful tools available to chemists for the elucidation of the structure of molecules. It is used to identify unknown substances, to characterize specific arrangements of atoms within molecules, and to study the dynamics of interactions between molecules in solution. Access to state-of-the-art NMR spectrometers is essential to chemists who are carrying out frontier research. The results from these NMR studies will have a positive impact in synthetic organic/inorganic chemistry, materials, the environment and biochemistry. This instrument will be an integral part of teaching as well as research.