Nanocapsules

化学系的大分子、超分子和纳米化学（MSN）项目支持Jerry L. Atwood在纳米胶囊设计和合成领域的贡献。 本研究的目标包括：（1）通过金属离子配位缝合的新胶囊的合成;（2）穿过胶囊壁的传输;（3）非常大的纳米胶囊的合成和（4）通过金属离子配位缝合的管组件。 对纳米胶囊组装中所涉及的自组装过程的理解的增加将在金属离子诱导的自组装的其他领域产生影响。 此外，开发各种尺寸的胶囊将为在受限环境中进行化学反应提供新的容器。 从胶囊到管的研究扩展涉及自组装过程的逻辑发展，该过程以胶囊的形成而终止，从而基本上在一维无限延伸。 除了提供新的基础知识外，这项关于纳米胶囊的研究还为靶向药物递送和催化等实际应用提供了机会。 此外，这项研究有助于科学人力资源的开发。 参与该计划的本科生，研究生和博士后研究员将接受培训，以推进研究，并了解这种基础研究是以目标为导向的。

The Macromolecular, Supramolecular and Nanochemistry (MSN) Program of the Division of Chemistry supports the work of Professor Jerry L. Atwood in the area of nanocapsule design and synthesis. The objectives of this research include: (1) the synthesis of new capsules seamed by metal-ion coordination; (2) transport across capsule walls; (3) the synthesis of very large nanocapsules and (4) tube assemblies seamed by metal-ion coordination. The increased understanding of the self-assembly process involved in the nanocapsule assembly will have ramifications in other areas of metal-ion induced self-assembly. In addition, the development of capsules over a range of sizes will provide new containers for carrying out chemical reactions in constrained environments. The extension of the research from capsules to tubes involves a logical development of the self-assembly process which terminates with the formation of a capsule to that which extends essentially infinitely in one dimension. In addition to providing new fundamental knowledge, this research on nanocapsules presents opportunities for practical applications such as targeted drug delivery and catalysis. Furthermore, this research contributes to the development of human resources in sciences. The undergraduate students, the graduate students, and the postdoctoral fellows involved in this program will be trained to carry the research forward with the understanding that such basic research is goal oriented.